Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742977 | 0.83 | ALDH1A1 (0.62) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL11815548 | 0.81 | ALDH1A1 (0.56) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL18188350 | 0.81 | ALDH1A1 (0.56) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL31392522 | 0.79 | ALDH1A1 (0.57) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL14414383 | 0.79 | ALDH1A1 (0.54) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL23885294 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL5787453 | 0.77 | ALDH1A1 (0.68) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL5787444 | 0.77 | ALDH1A1 (0.68) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL4275842 | 0.77 | ALDH1A1 (0.56) | ALDH1A1PDE10APOLBMEN1KMT2A | |
| SCHEMBL1332847 | 0.76 | ALDH1A1 (0.55) | ALDH1A1PDE10APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010145197-A1 | NOVEL 6-ARYLAMINO PYRIDONE SULFONAMIDES AND 6-ARYLAMINO PYRAZINONE SULFONAMDIES AS MEK INHIBITORS | CHEMIZON (BEIJING), LTD. (CN) | 2010-12-23 | — | — | WO | disclosed |
| US-3937831-A | CHLOROMETHYL NITROPYRIDINES AS ANTIMICROBIALS | THE DOW CHEMICAL COMPANY (US) | 1976-02-10 | — | — | US | disclosed |