SCHEMBL3801209

SCHEMBL3801209

NC1CC=Cc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.42
DPP4 P27487 1/20 0.36
KDM4E B2RXH2 2/20 0.35
TP53 P04637 2/20 0.35
CYP3A4 P08684 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR6 P50406 1/20 0.33
KDM1A O60341 7/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A3 Q01959 2/20 0.32
KDM1B Q8NB78 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20825180 0.79 HTR2A (0.39) HTR2ADPP4KDM4ETP53CYP3A4
SCHEMBL7214849 0.77 HTR2A (0.40) HTR2ADPP4KDM4ETP53CYP3A4
SCHEMBL7467393 0.77 HTR2A (0.38) HTR2ADPP4KDM4ETP53CYP3A4
SCHEMBL21158160 0.76 HTR2A (0.39) HTR2AKDM4ETP53CYP3A4HSD17B10
SCHEMBL6246911 0.74 HTR2A (0.38) HTR2AKDM4ETP53CYP3A4HSD17B10
SCHEMBL2528767 0.74 HTR2A (0.38) HTR2AKDM4ETP53CYP3A4HSD17B10
SCHEMBL10654456 0.74 HTR2A (0.38) HTR2AKDM4ETP53CYP3A4HSD17B10
SCHEMBL2875769 0.74 BRD4 (0.38) HTR2AKDM4ETP53CYP3A4HSD17B10
SCHEMBL6311766 0.74 HTR2A (0.38) HTR2AKDM4ETP53CYP3A4HSD17B10
SCHEMBL1974788 0.74 HTR2A (0.38) HTR2AKDM4ETP53CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200199481-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
CN-107001347-B Oxa- loop coil analog derivative, preparation method and its application in medicine 江苏恒瑞医药股份有限公司 2019-09-24 CN disclosed
CN-108290912-A Phosphinic acids peptide derivant as MMP-12 inhibitor 帝斯曼知识产权资产管理有限公司 2018-07-17 CN disclosed
CN-107001347-A Oxa- loop coil analog derivative, its preparation method and its in application pharmaceutically 江苏恒瑞医药股份有限公司 2017-08-01 CN disclosed
CN-106999535-A NF for treating diseases and disordersκInhibitors of B activity 拉金德拉·萨哈伊·巴特纳格尔 2017-08-01 CN disclosed
EP-1840399-B1 COLLAPSIBLE COLUMN NSK LTD (JP) 2014-06-18 EP disclosed
US-8741554-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-03 US disclosed
WO-2011068204-A1 BENZO[C]CARBAZOLE COMPOUND THAT HAS SUBSTITUENT BEARING PYRIDINE RING, AND ORGANIC ELECTROLUMINESCENT ELEMENT JNC株式会社 (JP) 2011-06-09 WO disclosed
US-20100304297-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-02 US disclosed
US-20050261141-A1 Rolling bearing, rolling bearing for fuel cell, compressor for fuel cell system and fuel cell system NSK LTD. 2005-11-24 US disclosed
US-6919301-B2 Grease composition and rolling apparatus NSK LTD. (JP) 2005-07-19 US disclosed
US-20030176298-A1 Grease composition and rolling apparatus NSK LTD. (JP) 2003-09-18 US disclosed
EP-0609905-A1 3-(Nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1994-08-10 EP disclosed
US-5225565-A Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1993-07-06 US disclosed
US-5182403-A Bactericides, treatment of AIDS THE UPJOHN COMPANY (US) 1993-01-26 US disclosed
US-5164510-A Bactericides THE UPJOHN COMPANY (US) 1992-11-17 US disclosed
EP-0434714-A1 IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES THE UPJOHN COMPANY (US) 1991-07-03 EP disclosed
WO-1990002744-A1 IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES THE UPJOHN COMPANY (US) 1990-03-22 WO disclosed
EP-0359418-A1 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1990-03-21 EP disclosed