Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790640 | 0.84 | HTR6 (0.33) | HTR2ADPP4HTR6 | |
| SCHEMBL290887 | 0.82 | HTR2A (0.39) | HTR2ADPP4KDM4EHTR2CHTR2B | |
| SCHEMBL10475434 | 0.80 | HTR2C (0.42) | SLC6A2HTR2CSLC6A3 | |
| SCHEMBL21158160 | 0.79 | HTR2A (0.39) | HTR2ACYP2D6CHRNB4CHRNA3KDM4E | |
| SCHEMBL10654456 | 0.77 | HTR2A (0.38) | HTR2ACYP2D6CHRNB4CHRNA3KDM4E | |
| SCHEMBL6246911 | 0.77 | HTR2A (0.38) | HTR2ACYP2D6CHRNB4CHRNA3KDM4E | |
| SCHEMBL2875769 | 0.77 | BRD4 (0.38) | HTR2ACYP2D6CHRNB4CHRNA3KDM4E | |
| SCHEMBL2528767 | 0.77 | HTR2A (0.38) | HTR2ACYP2D6CHRNB4CHRNA3KDM4E | |
| SCHEMBL6311766 | 0.77 | HTR2A (0.38) | HTR2ACYP2D6CHRNB4CHRNA3KDM4E | |
| SCHEMBL1974788 | 0.77 | HTR2A (0.38) | HTR2ACYP2D6CHRNB4CHRNA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610875-B1 | Forming bidentate ligands ofr assymetric catalysts; bromina-ting diaryldiol; esterifying with sulfonic acid; substituting cyano for bromine groups; coupling with a dicyclophosphine | RHODIA CHIMIE (FR) | 2003-08-26 | — | — | US | disclosed |