Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.58 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 6/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801250 | 1.00 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL16927091 | 0.89 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL470235 | 0.89 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL23140773 | 0.88 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL19221910 | 0.79 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL715583 | 0.76 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL16938681 | 0.75 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL470241 | 0.74 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL13075389 | 0.74 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL461806 | 0.74 | PIK3CD (0.76) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580797-B2 | Compounds | Glaxo Smith Kline Intellectual Property Development Limited (GB) | 2013-11-12 | — | — | US | disclosed |
| US-20100280045-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280045-A1 | NOVEL COMPOUNDS | PLK3, PLK1, PLK2 | PIK3CD 73/4885PIK3CA 70/4885PIK3CB 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.