Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795275 | 1.00 | CNR1 (0.42) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL3790072 | 0.87 | SLC6A3 (0.39) | CETPSLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9359639 | 0.82 | SLC6A3 (0.43) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL5680275 | 0.82 | CETP (0.42) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL8931548 | 0.82 | SLC6A3 (0.43) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL28187956 | 0.81 | CNR2 (0.50) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL28984518 | 0.80 | SLC6A3 (0.44) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL5678354 | 0.80 | CETP (0.41) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL9355996 | 0.80 | HDAC4 (0.47) | CNR1CNR2CETPSLC6A3SLC6A4 | |
| SCHEMBL28224003 | 0.80 | CNR1 (0.40) | CNR1CNR2CETPSLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130158111-A1 | Compositions and Methods for Depleting Mutant p53 | GEORGETOWN UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2010065329-A2 | NANOPARTICLES FOR CANCER TREATMENT | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20060241178-A1 | Compositions and methods for treating lung cancer | IMMUNEGUARD LLC (US) | 2006-10-26 | — | — | US | disclosed |
| WO-2004060365-A1 | COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER | AMERICAN HEALTH FOUNDATION (US) | 2004-07-22 | — | — | WO | disclosed |