Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372761 | 0.78 | PLAU (0.51) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3198127 | 0.76 | PLAU (0.52) | CA12CA1CA2CA3CA4 | |
| SCHEMBL8776195 | 0.76 | CA1 (0.39) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3189631 | 0.75 | USP2 (0.47) | CA1CA2ALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL3818324 | 0.71 | CA1 (0.47) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9264806 | 0.71 | TBXA2R (0.50) | — | |
| SCHEMBL9264814 | 0.71 | TBXAS1 (0.42) | SMN1; SMN2USP2HTT | |
| SCHEMBL9265240 | 0.71 | TBXA2R (0.51) | SMN1; SMN2USP2HTT | |
| SCHEMBL27278034 | 0.70 | MEN1 (0.59) | TSHRALDH1A1SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL9266823 | 0.70 | TBXA2R (0.41) | CA1CA2SMN1; SMN2USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408756-A1 | ALPHA-(N-BENZENESULFONAMIDO)CYCLOALKYL DERIVATIVES | Bristol-Myers Squibb Company (US) | 2012-01-25 | — | — | EP | disclosed |