Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.61 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511570 | 0.82 | GRM2 (0.61) | GRM2TDO2ADORA3ADORA2AADORA2B | |
| SCHEMBL13726598 | 0.82 | GRM2 (0.61) | GRM2TDO2 | |
| SCHEMBL8511014 | 0.82 | GRM2 (0.61) | GRM2TDO2 | |
| SCHEMBL9604229 | 0.82 | GRM2 (0.61) | GRM2TDO2 | |
| SCHEMBL8510414 | 0.79 | GRM2 (0.67) | GRM2TDO2 | |
| SCHEMBL25429341 | 0.78 | GRM2 (0.57) | GRM2 | |
| SCHEMBL31339740 | 0.78 | GRM2 (0.57) | GRM2 | |
| SCHEMBL9896222 | 0.77 | GRM2 (0.63) | GRM2TDO2ADORA3ADORA2AADORA2B | |
| SCHEMBL8509657 | 0.77 | GRM2 (0.54) | GRM2 | |
| SCHEMBL7803229 | 0.77 | GRM2 (0.51) | GRM2TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114726-A1 | AMINOBENZOTRIAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |