Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379676 | 0.88 | KDR (0.31) | — | |
| SCHEMBL379639 | 0.81 | — | — | |
| SCHEMBL4180787 | 0.69 | KDR (0.38) | — | |
| SCHEMBL379643 | 0.67 | CYP1A2 (0.58) | FGFR1PKMLMNAALDH1A1MAPT | |
| SCHEMBL379480 | 0.65 | CYP1A2 (0.63) | FGFR1PKMLMNAALDH1A1MAPT | |
| SCHEMBL380352 | 0.65 | HSD17B10 (0.48) | FGFR1PKMLMNAALDH1A1MAPT | |
| SCHEMBL4182628 | 0.64 | KDR (0.33) | — | |
| SCHEMBL5653235 | 0.63 | KCNH2 (0.35) | — | |
| SCHEMBL2678266 | 0.63 | CSF1R (0.49) | — | |
| SCHEMBL379642 | 0.63 | CLK4 (0.51) | LMNAALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968982-B1 | THIENO (3,2-C) PYRIDINE COMPOUNDS | XENTION LTD (GB) | 2012-01-25 | — | — | EP | claimed |