Benzene

Benzene

SCHEMBL3802036

NC(=O)NCc1ccccc1.NN.c1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.62
CYP2C9 P11712 2/20 0.62
CYP2D6 P10635 2/20 0.60
CYP1A2 P05177 1/20 0.60
TSHR P16473 1/20 0.60
RECQL P46063 1/20 0.59
GAA P10253 3/20 0.57
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55
ALDH1A1 P00352 3/20 0.54
ALOX12 P18054 2/20 0.54
HPGD P15428 1/20 0.54
GRIN2D O15399 2/20 0.53
GRIN3B O60391 2/20 0.53
GRIN1 Q05586 2/20 0.53
GRIN2A Q12879 2/20 0.53
GRIN2B Q13224 2/20 0.53
GRIN2C Q14957 2/20 0.53
GRIN3A Q8TCU5 2/20 0.53
SIGMAR1 Q99720 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81511 0.98 CYP2C19 (0.64) CYP2C19CYP2C9CYP2D6CYP1A2TSHR
Urea SCHEMBL11221937 0.96 CYP2C19 (0.62) CYP2C19CYP2C9CYP2D6CYP1A2TSHR
Ammonia Solution, Strong SCHEMBL5961420 0.96 CYP2C19 (0.62) CYP2C19CYP2C9CYP2D6CYP1A2TSHR
Hydrochloric Acid SCHEMBL17710406 0.96 CYP2C19 (0.62) CYP2C19CYP2C9CYP2D6CYP1A2TSHR
Dimethylamine SCHEMBL28098755 0.90 CYP2C9 (0.56) CYP2C19CYP2C9CYP2D6CYP1A2TSHR
Acrylic Acid SCHEMBL3948526 0.87 CYP2C19 (0.54) CYP2C19CYP2C9CYP2D6CYP1A2TSHR
SCHEMBL8245493 0.86 LMNA (0.64) CYP2C19CYP2C9TSHRRECQLGAA
Methacrylic Acid SCHEMBL3949680 0.85 CYP2C9 (0.53) CYP2C19CYP2C9CYP2D6CYP1A2TSHR
SCHEMBL28839185 0.83 HDAC6 (0.70) CYP2C19CYP2C9TSHRRECQLHPGD
SCHEMBL8513394 0.83 RECQL (0.59) CYP2C19CYP2C9CYP2D6CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090151598-A1 combination of passivating agents which evaporate or sublimate to temporarily prevent metal corrosion in packaging; a C6-10 aliphatic monocarboxylic acid;a C6-10 aliphatic dicarboxylic acid; a primary aromatic amide; an aliphatic ester of hydroxybenzoic acid; a benzimidazole EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2009-06-18 US claimed
US-7824482-B2 Vapor phase corrosion inhibitors and method for their production EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2010-11-02 US disclosed
US-20090151598-A1 combination of passivating agents which evaporate or sublimate to temporarily prevent metal corrosion in packaging; a C6-10 aliphatic monocarboxylic acid;a C6-10 aliphatic dicarboxylic acid; a primary aromatic amide; an aliphatic ester of hydroxybenzoic acid; a benzimidazole EXCOR KORROSIONSFORSCHUNG GMBH (DE) 2009-06-18 US disclosed