Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.58 |
| ▸ | PGR | P06401 | 12/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293028 | 0.88 | NR3C1 (0.58) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1635555 | 0.86 | NR3C1 (0.70) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1633869 | 0.86 | NR3C1 (0.66) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1634915 | 0.84 | NR3C1 (0.67) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL293016 | 0.82 | NR3C1 (0.55) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1634660 | 0.81 | NR3C1 (0.73) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL27754143 | 0.78 | NR3C1 (0.58) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL14340581 | 0.75 | NR3C1 (0.75) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL12762550 | 0.75 | NR3C1 (0.53) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL1634583 | 0.75 | NR3C1 (0.78) | NR3C1NR3C2PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190431-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | Bausch & Lomb Incorporated (US) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009023471-A2 | COMPOSITIONS COMPRISING A DISSOCIATED GLUCOCORTICOID RECEPTOR AGONIST FOR TREATING OR CONTROLLING ANTERIOR-SEGMENT INFLAMMATION | BAUSCH & LOMB INCORPORATED (US) | 2009-02-19 | — | — | WO | disclosed |