⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784939 | 0.65 | — | — | |
| SCHEMBL743705 | 0.65 | — | — | |
| SCHEMBL8688636 | 0.65 | — | — | |
| SCHEMBL1666716 | 0.65 | — | — | |
| SCHEMBL976280 | 0.65 | — | — | |
| SCHEMBL398311 | 0.65 | — | — | |
| SCHEMBL775060 | 0.65 | — | — | |
| SCHEMBL1082862 | 0.65 | — | — | |
| SCHEMBL19993292 | 0.64 | — | — | |
| SCHEMBL7179079 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807161-A1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | Merck Patent GmbH (DE) | 2014-12-03 | — | — | EP | claimed |
| WO-2014066506-A2 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-05-01 | — | — | WO | claimed |
| WO-2014002110-A1 | SUBSTITUTUED PYRAZOLE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF. | RALLIS INDIA LIMITED (IN) | 2014-01-03 | — | — | WO | claimed |
| WO-2013110309-A1 | TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-08-01 | — | — | WO | claimed |
| EP-1747206-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2007-01-31 | — | — | EP | claimed |
| WO-2007005510-A1 | N-HETEROARYLPIPERAZINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-11 | — | — | WO | claimed |
| WO-2005111003-A1 | AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-11-24 | — | — | WO | claimed |
| EP-3302465-A1 | TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES | Vertex Pharmaceuticals Incorporated (US) | 2018-04-11 | — | — | EP | disclosed |
| WO-2017168438-A1 | PROCESS FOR PREPARING PURE ALLYL PROTECTED KETO DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2017-10-05 | — | — | WO | disclosed |
| US-9751858-B2 | 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2017-09-05 | — | — | US | disclosed |
| WO-2016197009-A1 | TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-12-08 | — | — | WO | disclosed |
| US-20160237060-A1 | 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-08-18 | — | — | US | disclosed |
| EP-3024829-A1 | VASOPRESSIN-2 RECEPTOR AGONISTS | Ferring B.V. (NL) | 2016-06-01 | — | — | EP | disclosed |
| EP-0256981-A2 | Titanocenes and their use | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | disclosed |
| EP-0186626-A2 | Titanocenes and compositions curable by irradiation containing these titanocenes | CIBA-GEIGY AG (CH) | 1986-07-02 | — | — | EP | disclosed |
| EP-0185651-A1 | Intermediates for the production of antibacterial penem derivates | HOECHST UK LIMITED (GB) | 1986-06-25 | — | — | EP | disclosed |
| US-4559346-A | Certain N-octahydro-indolizinebenzamides and their use in treating psychosis, cardiac arrhythmia and hypertension | BEECHAM GROUP P.L.C. (GB) | 1985-12-17 | — | — | US | disclosed |
| US-4550111-A | BETA-ADRENERGIC BLOCKING AGENTS; DIURETICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-10-29 | — | — | US | disclosed |
| EP-0127412-A2 | Imidazolidinedione derivatives | PFIZER INC. (US) | 1984-12-05 | — | — | EP | disclosed |
| EP-0094744-A1 | Azabicyclobenzamides, their preparation and their pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1983-11-23 | — | — | EP | disclosed |