SCHEMBL784939

SCHEMBL784939

FC(F)(F)C1=CC=CC[CH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14335523 0.76
SCHEMBL1818106 0.75
SCHEMBL2189714 0.71
SCHEMBL18301588 0.66 ALDH1A1 (0.33)
SCHEMBL10874064 0.66
SCHEMBL2084086 0.65
SCHEMBL18715549 0.65
SCHEMBL380209 0.65
SCHEMBL18970423 0.63
SCHEMBL11017957 0.63 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210280795-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-09-09 US claimed
EP-3230440-A1 COMPOSITIONS AND METHODS FOR NEURONAL DIFFERENTIATION OF CELLS Northern Sydney Local Health District (AU) 2017-10-18 EP claimed
WO-2016090408-A1 COMPOSITIONS AND METHODS FOR NEURONAL DIFFERENTIATION OF CELLS NORTHERN SYDNEY LOCAL HEALTH DISTRICT (AU) 2016-06-16 WO claimed
EP-2800800-A1 TRACERS AND METHOD OF MARKING LIQUIDS Johnson Matthey Public Limited Company (GB) 2014-11-12 EP claimed
WO-2013102766-A1 TRACERS AND METHOD OF MARKING LIQUIDS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2013-07-11 WO claimed
JP-2007506696-A 2007-03-22 JP claimed
EP-1667980-A1 1,4-DISUBSTITUTED ISOQUINOLINE DERIVATIVES AS RAF-KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES Novartis AG (CH) 2006-06-14 EP claimed
EP-1658305-A1 NOVEL FUSIDIC ACID DERIVATIVES Leo Pharma A/S (DK) 2006-05-24 EP claimed
US-7037931-B2 Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia JANSSEN PHARMACEUTICA N.V. (BE) 2006-05-02 US claimed
WO-2005028444-A1 1,4-DISUBSTITUTED ISOQUINILONE DERIVATIVES AS RAF-KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES NOVARTIS AG (CH) 2005-03-31 WO claimed
WO-2005007669-A1 NOVEL FUSIDIC ACID DERIVATIVES LEO PHARMA A/S (DK) 2005-01-27 WO claimed
EP-0365397-A2 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER INDUSTRIE ET SANTE (FR) 1990-04-25 EP claimed
EP-0136995-B1 PREPARATION OF 2-(METHYLTHIOMETHYL)-6-(TRIFLUOROMETHYL) ANILINE FROM ORTHO-AMINOBENZOTRIFLUORIDE Monsanto Company (US) 1987-10-28 EP claimed
US-9751858-B2 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals SANOFI (FR) 2017-09-05 US disclosed
US-20160237060-A1 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS SANOFI (FR) 2016-08-18 US disclosed
US-9353068-B2 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals SANOFI (FR) 2016-05-31 US disclosed
EP-0365397-B1 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER IND & SANTE (FR) 1994-09-28 EP disclosed
EP-0365397-A2 Beta-D-phenyl thioxylosides, method for their preparation and their use in therapy FOURNIER INDUSTRIE ET SANTE (FR) 1990-04-25 EP disclosed
EP-0268273-A2 Process for the preparation of 2-substituted-1,4-dihydro-pyridines WARNER-LAMBERT COMPANY (US) 1988-05-25 EP disclosed
US-3989744-A STIMULATES SMOOTH MUSCLES, PROSTAGLANDINS MILES LABORATORIES, INC. (US) 1976-11-02 US disclosed