Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1267388 | 1.00 | CYP19A1 (0.45) | CYP19A1ADORA3ARMAOBKDM4E | |
| SCHEMBL30064231 | 1.00 | CYP19A1 (0.45) | CYP19A1ADORA3ARMAOBKDM4E | |
| SCHEMBL25567835 | 0.88 | CYP3A4 (0.50) | CYP19A1ADORA3ARMAOBHSD17B10 | |
| SCHEMBL20047288 | 0.83 | CFTR (0.48) | CYP19A1ARCFTR | |
| SCHEMBL7048656 | 0.82 | CYP19A1 (0.60) | CYP19A1ARMAOBHSD17B10CYP3A4 | |
| SCHEMBL1933778 | 0.82 | CYP19A1 (0.60) | CYP19A1ARMAOBHSD17B10CYP3A4 | |
| SCHEMBL4365834 | 0.82 | AR (0.54) | CYP19A1ADORA3ARMAOBHSD17B10 | |
| SCHEMBL1933397 | 0.81 | CYP19A1 (0.44) | CYP19A1ARMAOBMAOA | |
| SCHEMBL10366584 | 0.80 | MAOB (0.41) | CYP19A1ADORA3ARMAOBKDM4E | |
| SCHEMBL11093832 | 0.79 | CYP19A1 (0.42) | CYP19A1ADORA3ARMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408927-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105851-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-23 | — | — | WO | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
| EP-1778850-A2 | PRODUCTION OF FLAVONOIDS BY RECOMBINANT MICROORGANISMS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006010117-A2 | PRODUCTION OF FLAVONOIDS BY RECOMBINANT MICROORGANISMS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2006-01-26 | — | — | WO | disclosed |