SCHEMBL380309

SCHEMBL380309

NC(N)([C]=O)CCCC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776963 0.98
SCHEMBL10804336 0.77 FDPS (0.38)
SCHEMBL131287 0.71
SCHEMBL835617 0.69
SCHEMBL3499126 0.69
SCHEMBL835553 0.69
SCHEMBL1676791 0.67
SCHEMBL2154219 0.67
SCHEMBL2153675 0.67
SCHEMBL2153961 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408927-A1 PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2012-01-25 EP disclosed
CN-102307586-A Compounds and methods for the treatment of autoimmune and inflammatory disease TRINITY COLLEGE DUBLIN 2012-01-04 CN disclosed
WO-2010105851-A1 PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-23 WO disclosed
EP-0959902-A4 RECOMBINANT MYCOBACTERIA AUXOTROPHIC FOR DIAMINOPIMELATE EINSTEIN COLL MED (US) 2001-11-28 EP disclosed
US-6221364-B1 Recombinant mycobacteria auxotrophic for diaminopimelate ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY 2001-04-24 US disclosed
EP-0959902-A1 RECOMBINANT MYCOBACTERIA AUXOTROPHIC FOR DIAMINOPIMELATE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, a division of YESHIVA UNIVERSITY (US) 1999-12-01 EP disclosed
WO-1998020898-A1 RECOMBINANT MYCOBACTERIA AUXOTROPHIC FOR DIAMINOPIMELATE ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY (US) 1998-05-22 WO disclosed
US-5420347-A Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine PFIZER INC. (US) 1995-05-30 US disclosed
US-5371187-A Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, and processes and intermediates therefor PFIZER INC. (US) 1994-12-06 US disclosed
US-5286904-A Processes and intermediates for N-(S-3-alkyl-heptanoyl)-D-gamma-glutamyl-glycyl-D-alanine PFIZER INC. (US) 1994-02-15 US disclosed
EP-0227306-A2 Peptide immunostimulants PFIZER INC. (US) 1987-07-01 EP disclosed
US-4619915-A ANTIINFECTION AGENTS PFIZER INC. (US) 1986-10-28 US disclosed
EP-0178845-A2 Peptide-substituted heterocyclic immunostimulants PFIZER INC. (US) 1986-04-23 EP disclosed
US-4565653-A Acyltripeptide immunostimulants PFIZER INC. (US) 1986-01-21 US disclosed
EP-0157572-A2 Acyltripeptide immunostimulants PFIZER INC. (US) 1985-10-09 EP disclosed
US-4539155-A New peptide, process for preparation thereof and use thereof FUISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1985-09-03 US disclosed
US-4370265-A N-ACETYLMURAMYL-L-ALANYL-D-GLUTAMIC ACID AGENCE NATIONALE DE VALORISATION (FR) 1983-01-25 US disclosed
US-4235771-A ACYL-MURAMIC ACID WITH PEPTIDE CHAIN LINKED THERETO AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1980-11-25 US disclosed
EP-0011283-A1 New lactyl tetrapeptide, processes for preparation thereof and pharmaceutical compositions containing it FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-05-28 EP disclosed
US-4186194-A Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1980-01-29 US disclosed