SCHEMBL3804100

SCHEMBL3804100

C=CC(F)C(=C)C(F)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4405927 0.74
SCHEMBL4562799 0.72
SCHEMBL3635796 0.71
SCHEMBL278124 0.71
SCHEMBL8642386 0.69 LMNA (0.32)
SCHEMBL592111 0.67
SCHEMBL471880 0.67
Bicarbonate SCHEMBL28615380 0.67 LMNA (0.32)
SCHEMBL4665260 0.67
SCHEMBL2989676 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0831770-B1 CONTINUOUS FLUOROCHEMICAL MICRODISPERSIONS FOR THE DELIVERY OF PHARMACEUTICAL AGENTS ALLIANCE PHARMA (US) 2000-08-16 EP claimed
EP-0655069-B1 AMPHIPHILIC COMPOUNDS DERIVED FROM AMINO ACIDS OR PEPTIDES, THEIR METHODS OF SYNTHESIS AND THEIR APPLICATION AS DRUG DELIVERY SYSTEMS ALLIANCE PHARMA (US) 1999-11-03 EP claimed
EP-0666736-B1 STABILIZATION OF FLUOROCARBON EMULSIONS ALLIANCE PHARMA (US) 1996-12-18 EP claimed
EP-0655069-A1 AMPHIPHILIC COMPOUNDS DERIVED FROM AMINO ACIDS OR PEPTIDES, THEIR METHODS OF SYNTHESIS AND THEIR APPLICATION AS DRUG DELIVERY SYSTEMS ALLIANCE PHARMACEUTICAL CORP. (US) 1995-05-31 EP claimed
WO-1994003468-A1 AMPHIPHILIC COMPOUNDS DERIVED FROM AMINO ACIDS OR PEPTIDES, THEIR METHODS OF SYNTHESIS AND THEIR APPLICATION AS DRUG DELIVERY SYSTEMS S.A. A.T.T.A. APPLICATIONS ET TRANSFERTS DE TECHNOLOGIES AVANCEES (FR) 1994-02-17 WO claimed
US-8748497-B2 Optimized fluorocarbon emulsions for blood substitutes and other therapeutic uses ALLIANCE PHARMACEUTICAL CORP. (US) 2014-06-10 US disclosed
EP-1740189-B1 LUNG SURFACTANT SUPPLEMENTS CENTRE NAT RECH SCIENT (FR) 2012-06-13 EP disclosed
US-20100298445-A1 Optimized Fluorocarbon Emulsions for Blood Substitutes and Other Therapeutic Uses ALLIANCE PHARMACEUTICAL CORP 2010-11-25 US disclosed
EP-2034959-A2 OPTIMIZED FLUOROCARBON EMULSIONS FOR BLOOD SUBSTITUTES AND OTHER THERAPEUTIC USES Alliance Pharmaceutical Corp (US) 2009-03-18 EP disclosed
US-20080019926-A1 Lung Surfactant Supplements UNIVERSITE LOUIS PASTEUR INDUSTRIE (FR) 2008-01-24 US disclosed
WO-2007139827-A2 OPTIMIZED FLUOROCARBON EMULSIONS FOR BLOOD SUBSTITUTES AND OTHER THERAPEUTIC USES ALLIANCE PHARMACEUTICAL CORP. (US) 2007-12-06 WO disclosed
US-20050256211-A9 Patient oxygenation using stabilized fluorocarbon emulsions PFC THERAPEUTICS, LLC 2005-11-17 US disclosed
US-20040068020-A1 Patient oxygenation using stabilized fluorocarbon emulsions WEERS JEFFRY GREG (US) 2004-04-08 US disclosed
US-20020065326-A1 Patient oxygenation using stabilized fluorocarbon emulsions WEERS JEFFRY GREG (US) 2002-05-30 US disclosed
US-6204296-B1 INTRAVENOUSLY ADMINISTERING TO SAID PATIENT A FLUOROCARBON EMULSION COMPRISING AN EMULSIFYING AGENT, PERFLUOROOCTYL BROMIDE AND PERFLUORODECYL BROMIDE. ALLIANCE PHARMACEUTICAL CORP. 2001-03-20 US disclosed
EP-0689422-B1 FLUOROCARBON EMULSIONS WITH REDUCED PULMONARY GAS-TRAPPING PROPERTIES ALLIANCE PHARMA (US) 1999-07-14 EP disclosed
US-5914352-A Methods for the use of stabilized fluorocarbon emulsions ALLIANCE PHARMACEUTICAL CORP. (US) 1999-06-22 US disclosed
US-5635538-A AQUEOUS PHASE, EMULSIFYING AGENT, AND LIQUID FLUOROCARBON PHASE CONTAINING MIXTURE OF AT LEAST TWO FLUOROCARBONS, AT LEAST ONE FLUOROCARBON HAS COVALENTLY ATTACHED LIPOPHILIC MOIETY ALLIANCE PHARMACEUTICAL CORP. (US) 1997-06-03 US disclosed
US-5628930-A STORAGE STABILITY ALLIANCE PHARMACEUTICAL CORP. (US) 1997-05-13 US disclosed
EP-0666736-B1 STABILIZATION OF FLUOROCARBON EMULSIONS ALLIANCE PHARMA (US) 1996-12-18 EP disclosed