Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.57 |
| ▸ | CNR2 | P34972 | 4/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080887 | 1.00 | ALOX15 (0.57) | ALOX15CNR2CNR1CHEK1 | |
| SCHEMBL4090731 | 0.91 | CNR2 (0.53) | ALOX15CNR2CNR1CHEK1 | |
| SCHEMBL3810752 | 0.91 | CNR2 (0.53) | ALOX15CNR2CNR1CHEK1 | |
| SCHEMBL4091079 | 0.90 | CHEK1 (0.54) | ALOX15CNR2CNR1CHEK1 | |
| SCHEMBL4092591 | 0.86 | CNR2 (0.60) | ALOX15CNR2CNR1 | |
| SCHEMBL3804561 | 0.86 | CNR2 (0.60) | ALOX15CNR2CNR1 | |
| SCHEMBL3749679 | 0.85 | CNR2 (0.62) | CNR2CHEK1 | |
| SCHEMBL4095727 | 0.84 | CNR2 (0.64) | ALOX15CNR2 | |
| SCHEMBL3800992 | 0.84 | CNR2 (0.64) | ALOX15CNR2 | |
| SCHEMBL4095472 | 0.83 | CNR2 (0.59) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176219-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009009550-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | WO | disclosed |