Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27832982 | 0.89 | TSHR (0.33) | KCNN4TDP1GAATSHR | |
| SCHEMBL115842 | 0.85 | CYP3A4 (0.39) | KCNN4CYP3A4TDP1CYP2C19TP53 | |
| SCHEMBL15485017 | 0.84 | KCNN4 (0.32) | KCNN4CYP3A4TDP1GAAALOX12 | |
| SCHEMBL27851234 | 0.84 | KCNN4 (0.32) | KCNN4CYP3A4TDP1GAAALOX12 | |
| SCHEMBL9249942 | 0.84 | CYP3A4 (0.32) | CYP3A4TDP1 | |
| SCHEMBL28791530 | 0.83 | CYP3A4 (0.35) | KCNN4CYP3A4TDP1TP53 | |
| SCHEMBL29514487 | 0.83 | CYP3A4 (0.38) | KCNN4CYP3A4TDP1CYP2C19 | |
| SCHEMBL23843916 | 0.82 | CYP3A4 (0.33) | CYP3A4TDP1 | |
| SCHEMBL15484236 | 0.82 | GAA (0.35) | KCNN4CYP3A4TDP1GAAALOX12 | |
| SCHEMBL660489 | 0.82 | KCNN4 (0.33) | KCNN4CYP3A4TDP1GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398764-A1 | METHOD FOR PRODUCING 2-AMINOBIPHENYLENE | BASF SE (DE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094736-A1 | METHOD FOR PRODUCING 2-AMINOBIPHENYLENE | BASF SE (DE) | 2010-08-26 | — | — | WO | disclosed |