Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15484236 | 0.96 | GAA (0.35) | KCNN4CYP3A4TDP1GAAALOX12 | |
| SCHEMBL15485001 | 0.92 | KCNN4 (0.31) | KCNN4CYP3A4TDP1GAAALOX12 | |
| SCHEMBL15484268 | 0.89 | GAA (0.33) | TDP1GAAALOX12CYP2C19 | |
| SCHEMBL28130666 | 0.86 | GAA (0.36) | GAACYP2C19TP53 | |
| SCHEMBL5868726 | 0.85 | CYP3A4 (0.38) | KCNN4CYP3A4TDP1TP53 | |
| SCHEMBL15484304 | 0.84 | GAA (0.34) | KCNN4CYP3A4TDP1GAA | |
| SCHEMBL664879 | 0.83 | CYP3A4 (0.36) | KCNN4CYP3A4TDP1TP53 | |
| SCHEMBL9190778 | 0.82 | CYP3A4 (0.43) | KCNN4CYP3A4TDP1GAA | |
| SCHEMBL15485017 | 0.82 | KCNN4 (0.32) | KCNN4CYP3A4TDP1GAAALOX12 | |
| SCHEMBL27851234 | 0.82 | KCNN4 (0.32) | KCNN4CYP3A4TDP1GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829248-B2 | Method for recovery and recycle of ruthenium homogeneous catalysts | EASTMAN CHEMICAL COMPANY (US) | 2014-09-09 | — | — | US | claimed |
| EP-2605856-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | Eastman Chemical Company (US) | 2013-06-26 | — | — | EP | claimed |
| WO-2012024253-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-02-23 | — | — | WO | claimed |
| US-20120046481-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2012-02-23 | — | — | US | claimed |
| CN-104203884-B | Passivation of homogeneous hydrogenation catalysts for the production of ethylene glycol | 伊士曼化工公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-103153463-B | The method of recovery and recycle of ruthenium homogeneous catalyst | EASTMAN CHEMICAL CO. (US) | 2015-09-09 | — | — | CN | disclosed |
| EP-2141142-B1 | METHOD FOR PRODUCING ALCOHOL BY HYDROGENATING LACTONE OR CARBOXYLIC ACID ESTER IN LIQUID PHASE | TAKASAGO PERFUMERY CO LTD (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-8969632-B2 | Passivation of a homogeneous hydrogenation catalyst for the production of ethylene glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| CN-104203884-A | Passivation of homogeneous hydrogenation catalysts for the production of ethylene glycol | EASTMAN CHEM CO | 2014-12-10 | — | — | CN | disclosed |
| US-8829248-B2 | Method for recovery and recycle of ruthenium homogeneous catalysts | EASTMAN CHEMICAL COMPANY (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130253230-A1 | PASSIVATION OF A HOMOGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | EASTMAN CHEMICAL COMPANY (US) | 2013-09-26 | — | — | US | disclosed |
| EP-2605856-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | Eastman Chemical Company (US) | 2013-06-26 | — | — | EP | disclosed |
| EP-2141142-A1 | METHOD FOR PRODUCING ALCOHOL BY HYDROGENATING LACTONE AND CARBOXYLIC ACID ESTER IN LIQUID PHASE | Takasago International Corporation (JP) | 2010-01-06 | — | — | EP | disclosed |
| US-7105590-B2 | Phenolfree stabilization of polyolefins | CLARIANT FINANCE (BVI) LIMITED (VG) | 2006-09-12 | — | — | US | disclosed |
| US-7083743-B2 | Mixture of phosphanes and chromane derivatives | CLARIANT FINANCE (BVI) LIMITED (VG) | 2006-08-01 | — | — | US | disclosed |
| US-7067569-B2 | Mixtures of phosphorus-containing compounds used as polymer stabilizers | CLARIANT FINANCE (BVI) LIMITED (VG) | 2006-06-27 | — | — | US | disclosed |
| EP-1303563-B1 | MIXTURES OF PHOSPHORUS-CONTAINING COMPOUNDS USED AS POLYMER STABILISERS | CLARIANT FINANCE BVI LTD (VG) | 2005-11-02 | — | — | EP | disclosed |
| EP-1417257-B1 | PHENOLFREE STABILIZATION OF POLYOLEFINS | CLARIANT FINANCE BVI LTD (VG) | 2005-02-09 | — | — | EP | disclosed |
| US-20040186207-A1 | Phenolfree stabilization of polyolefins | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-09-23 | — | — | US | disclosed |
| US-20030187111-A1 | Mixtures of phosphorus-containing compounds used as polymer stabilizers | CLARIANT FINANCE (BVI) LIMITED (VG) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253230-A1 | PASSIVATION OF A HOMOGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | HPD, TALDO1, GRHPR | KCNN4 3036/4885CYP3A4 402/4885TDP1 3630/4885 |
| US-20120046481-A1 | METHOD FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENEOUS CATALYSTS | GRHPR, DERA, APEH | KCNN4 3617/4885CYP3A4 1612/4885TDP1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.