SCHEMBL3804442

CC(=O)OC[C@H]1O[C@H](O[C@H]2[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](On3cc(COC4CC[C@@]5(C)C(CC[C@H]6[C@@H]7CC[C@H]([C@H](C)CCCC(C)C)[C@@]7(C)CC[C@@H]65)C4)nn3)O[C@@H]2COC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

nearest known ligand 0.62

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	HPSE	Q9Y251	17/20	0.62

▸	FGF1	P05230	11/20	0.62

▸	FGF2	P09038	11/20	0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12591000	0.79	HPSE (0.64)	HPSEFGF1FGF2
SCHEMBL2058821	0.77	HPSE (0.59)	HPSEFGF1FGF2
SCHEMBL12590996	0.77	HPSE (0.59)	HPSEFGF1FGF2
SCHEMBL2059338	0.76	HPSE (0.54)	HPSEFGF1FGF2
SCHEMBL11421869	0.76	VDR (0.53)	HPSEFGF1FGF2
SCHEMBL24017723	0.76	CDC25A (0.61)	HPSEFGF1FGF2
SCHEMBL21340268	0.76	CDC25A (0.61)	HPSEFGF1FGF2
SCHEMBL20004930	0.76	CDC25A (0.61)	HPSEFGF1FGF2
SCHEMBL21340577	0.74	HPSE (0.65)	HPSEFGF1FGF2
SCHEMBL24017722	0.74	CDC25A (0.60)	HPSEFGF1FGF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2205616-A1	NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES	Progen Pharmaceuticals Limited (AU)	2010-07-14	—	—	EP	disclosed
WO-2009049370-A1	NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES	PROGEN PHARMACEUTICALS LIMITED (AU)	2009-04-23	—	—	WO	disclosed