Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.66 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.56 |
| ▸ | PLK4 | O00444 | 1/20 | 0.55 |
| ▸ | CIT | O14578 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | GAK | O14976 | 1/20 | 0.55 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.55 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.55 |
| ▸ | BUB1 | O43683 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.55 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.55 |
| ▸ | STK17B | O94768 | 1/20 | 0.55 |
| ▸ | STK10 | O94804 | 1/20 | 0.55 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839619 | 0.89 | EGFR (0.70) | EGFRERBB2PLK4CITAURKA | |
| SCHEMBL186330 | 0.88 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL29623474 | 0.88 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL2762886 | 0.86 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL209223 | 0.85 | EGFR (0.68) | EGFRERBB2PLK4CITAURKA | |
| SCHEMBL29623516 | 0.85 | EGFR (0.68) | EGFRERBB2PLK4CITAURKA | |
| SCHEMBL29623562 | 0.85 | EGFR (0.83) | EGFRERBB2FLT1KDR | |
| SCHEMBL210910 | 0.85 | EGFR (0.83) | EGFRERBB2FLT1KDR | |
| SCHEMBL29623442 | 0.85 | EGFR (0.80) | EGFRERBB2AURKAPDGFRBFLT1 | |
| SCHEMBL118997 | 0.85 | EGFR (0.80) | EGFRERBB2AURKAPDGFRBFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408500-A1 | DISPENSING DEVICE, STORAGE DEVICE AND METHOD FOR DISPENSING A FORMULATION | Boehringer Ingelheim International GmbH (DE) | 2012-01-25 | — | — | EP | disclosed |
| EP-2326374-A1 | INHALER | Boehringer Ingelheim International GmbH (DE) | 2011-06-01 | — | — | EP | disclosed |