SCHEMBL380666

SCHEMBL380666

c1c[nH]c2cccc-2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3824245 0.97 HDAC6 (0.48)
SCHEMBL80142 0.92 HDAC1 (0.48)
SCHEMBL9419852 0.91 HDAC6 (0.57)
SCHEMBL27515517 0.89 HDAC1 (0.47)
SCHEMBL28212557 0.89 HDAC1 (0.47)
Fluoride SCHEMBL30394298 0.89 HDAC1 (0.47)
SCHEMBL27882289 0.89 HDAC1 (0.47)
SCHEMBL20510943 0.89 CNR1 (0.47)
SCHEMBL27462334 0.87 HDAC1 (0.50)
Fluoride SCHEMBL27588272 0.85 HDAC1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 864 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2026-05-28 US claimed
EP-3185329-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-04-22 EP claimed
US-20250223285-A1 NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS JACOBIO PHARMACEUTICALS CO LTD (CN) 2025-07-10 US claimed
CN-120118074-A PI3K alpha inhibitor compound, pharmaceutical composition and application thereof 长春金赛药业有限责任公司 2025-06-10 CN claimed
WO-2025030002-A2 DGK TARGETING COMPOUNDS AND USES THEREOF ARVINAS OPERATIONS, INC. (US) 2025-02-06 WO claimed
WO-2024134683-A1 Novel process for the preparation of intermediate compounds used in the treatment of migraine MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2024-06-27 WO claimed
EP-3185328-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2024-05-22 EP claimed
CN-118039263-A High-voltage cable buffer layer, preparation method thereof and high-voltage cable 广东电网有限责任公司广州供电局 2024-05-14 CN claimed
EP-3185332-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2024-05-01 EP claimed
CN-117825266-A Quantitative test method for binding force of fiber coating 中国科学院苏州纳米技术与纳米仿生研究所 2024-04-05 CN claimed
WO-2011069134-A2 SUPPORTED OLEFIN METATHESIS CATALYSTS MATERIA, INC. (US) 2011-06-09 WO claimed
US-20100152237-A1 BIS-PYRINDINO CONTAINING COMPOUNDS FOR THE USE IN THE TREATMENT OF CNS PATHOLOGIES UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2010-06-17 US claimed
US-7598330-B2 Cross-metathesis of olefins directly substituted with an electron-withdrawing group using transition metal carbene catalysts CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2009-10-06 US claimed
US-20080287490-A1 Bis-pyridino containing compounds for the use in the treatment of CNS pathologies UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2008-11-20 US claimed
EP-1497299-A4 CROSS-METATHESIS OF OLEFINS DIRECTLY SUBSTITUTED WITH AN ELECTRON-WITHDRAWING GROUP USING TRANSITION METAL CARBENE CATALYSTS CALIFORNIA INST OF TECHN (US) 2006-08-02 EP claimed
US-20050261334-A1 Bis-pyridino containing compounds for the use in the treatment of CNS pathologies UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2005-11-24 US claimed
EP-1497299-A2 CROSS-METATHESIS OF OLEFINS DIRECTLY SUBSTITUTED WITH AN ELECTRON-WITHDRAWING GROUP USING TRANSITION METAL CARBENE CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2005-01-19 EP claimed
US-20030236427-A1 Cross-metathesis of olefins directly substituted with an electron-withdrawing group using transition metal carbene catalysts NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-12-25 US claimed
US-20030225142-A1 Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2003-12-04 US claimed
WO-2003087167-A2 CROSS-METATHESIS OF OLEFINS DIRECTLY SUBSTITUTED WITH AN ELECTRON-WITHDRAWING GROUP USING TRANSITION METAL CARBENE CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-10-23 WO claimed