Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380666 | 0.89 | — | — | |
| SCHEMBL18821909 | 0.89 | HDAC6 (0.45) | CNR1HDAC1HDAC6NT5ECSF1R | |
| Hydrochloric Acid SCHEMBL3824245 | 0.86 | HDAC6 (0.48) | CNR1HDAC1HDAC6NT5EIDO1 | |
| SCHEMBL237434 | 0.86 | IDO1 (0.56) | CNR1IDO1CSF1RNOTUM | |
| SCHEMBL7292924 | 0.84 | IDO1 (0.46) | CNR1HDAC1HDAC6IDO1 | |
| SCHEMBL7762234 | 0.84 | IDO1 (0.46) | CNR1NT5EIDO1 | |
| SCHEMBL16236283 | 0.84 | MAOA (0.50) | CNR1BACE1 | |
| SCHEMBL11434632 | 0.84 | NT5E (0.57) | CNR1NT5E | |
| SCHEMBL30469333 | 0.84 | MAOA (0.50) | CNR1BACE1 | |
| SCHEMBL30460063 | 0.84 | IDO1 (0.55) | CNR1IDO1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11618745-B2 | Unsymmeirical salts, CCC-NHC pincer metal complexes, and methods of making the same | MISSISSIPPI STATE UNIVERSITY (US) | 2023-04-04 | — | — | US | disclosed |
| US-20210179588-A1 | UNSYMMETRICAL SALTS, CCC-NHC PINCER METAL COMPLEXES, AND METHODS OF MAKING THE SAME | MISSISSIPPI STATE UNIVERSITY | 2021-06-17 | — | — | US | disclosed |
| US-10927099-B2 | Unsymmetric CCC-NHC pincer metal complexes and methods of use thereof | MISSISSIPPI STATE UNIVERSITY (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200095228-A1 | UNSYMMETRIC CCC-NHC PINCER METAL COMPLEXES AND METHODS OF USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2020-03-26 | — | — | US | disclosed |
| EP-3600656-A1 | UNSYMMETRICAL SALTS, CCC-NHC PINCER METAL COMPLEXES, AND METHODS OF MAKING THE SAME | Mississippi State University (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018175659-A1 | UNSYMMETRICAL SALTS, CCC-NHC PINCER METAL COMPLEXES, AND METHODS OF MAKING THE SAME | MISSISSIPPI STATE UNIVERSITY (US) | 2018-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11618745-B2 | Unsymmeirical salts, CCC-NHC pincer metal complexes, and methods of making the same | NDC1, INO80C, HLCS | CNR1 690/4885HDAC1 485/4885HDAC6 1706/4885 |
| US-20200095228-A1 | UNSYMMETRIC CCC-NHC PINCER METAL COMPLEXES AND METHODS OF USE THEREOF | NDC1, INO80C, KCNC1 | CNR1 764/4885HDAC1 423/4885HDAC6 1675/4885 |
| US-20210179588-A1 | UNSYMMETRICAL SALTS, CCC-NHC PINCER METAL COMPLEXES, AND METHODS OF MAKING THE SAME | NDC1, INO80C, KCNC1 | CNR1 576/4885HDAC1 489/4885HDAC6 1770/4885 |
| US-10927099-B2 | Unsymmetric CCC-NHC pincer metal complexes and methods of use thereof | NDC1, INO80C, KCNC1 | CNR1 764/4885HDAC1 423/4885HDAC6 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.