Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396406 | 1.00 | KMT2A (0.73) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL28685764 | 1.00 | KMT2A (0.73) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL24308948 | 0.89 | KMT2A (0.79) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL23658897 | 0.89 | KMT2A (0.64) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL23658968 | 0.89 | KMT2A (0.64) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL15715540 | 0.86 | KMT2A (0.69) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL3787871 | 0.82 | KMT2A (0.52) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL31326108 | 0.82 | MEN1 (0.56) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL6828371 | 0.80 | KMT2A (0.61) | KMT2AMEN1L3MBTL1HTTALDH1A1 | |
| SCHEMBL23658965 | 0.79 | KMT2A (0.60) | KMT2AMEN1L3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133412-B | Preparation method of chiral 1, 2-bis [ (2-methoxyphenyl) phenylphosphinyl ] ethane | 河南工程学院 | 2023-11-07 | — | — | CN | claimed |
| US-8471067-B2 | Stereoselective preparation of P-chiral four-co-ordinated phosphorus compound (o-Tolylphenylmethylphosphine oxide) by reacting chiral alcohol, chiral amine or chiral thiol, with P-chiral three-co-ordinated phosphorus compound, in presence of electrophile | UNIVERSITY COLLEGE DUBLIN (IE) | 2013-06-25 | — | — | US | claimed |
| WO-2010004278-A1 | METHOD FOR INCREASING THE ENANTIOMERIC EXCESS OF CHIRAL PHOSPHINE OXIDES, SULPHIDES, IMIDES AND BORANES | CELTIC CATALYSTS LIMITED (IE) | 2010-01-14 | — | — | WO | claimed |
| US-20080255391-A1 | Chiral Phosphorus Compounds | UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY OF IRELAND (IE) | 2008-10-16 | — | — | US | claimed |
| JP-2008501010-A | — | — | 2008-01-17 | — | — | JP | claimed |
| EP-1751170-A1 | CHIRAL PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2007-02-14 | — | — | EP | claimed |
| WO-2005118603-A1 | CHIRAL PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2005-12-15 | — | — | WO | claimed |
| US-4008281-A | BIS-PHOSPHINE | MONSANTO COMPANY (US) | 1977-02-15 | — | — | US | claimed |
| CN-117843679-A | Fluorine-containing biphosphine compound and preparation method thereof | 四川轻化工大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117447464-A | Method for producing optically active compound | 首日生物制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114133412-B | Preparation method of chiral 1, 2-bis [ (2-methoxyphenyl) phenylphosphinyl ] ethane | 河南工程学院 | 2023-11-07 | — | — | CN | disclosed |
| CN-114133412-B | Preparation method of chiral 1, 2-bis [ (2-methoxyphenyl) phenylphosphinyl ] ethane | 河南工程学院 | 2023-11-07 | — | — | CN | disclosed |
| CN-114133412-B | Preparation method of chiral 1, 2-bis [ (2-methoxyphenyl) phenylphosphinyl ] ethane | 河南工程学院 | 2023-11-07 | — | — | CN | disclosed |
| CN-111032047-B | Method for producing optically active compound | 多特疗法-1公司 | 2023-10-27 | — | — | CN | disclosed |
| WO-2005118603-A1 | CHIRAL PHOSPHORUS COMPOUNDS | UNIVERSITY COLLEGE DUBLIN (IE) | 2005-12-15 | — | — | WO | disclosed |
| US-4939288-A | Catalytic hydrogenation | MONSANTO COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0229944-A2 | Novel tetrahydroisoquinoline derivatives | SYNTEX (U.S.A.) INC. (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4220590-A | OPTICALLY ACTIVE BIS PHOSPHINE COMPOUNDS | MONSANTO COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4142992-A | ASYMMETRIC CATALYSIS | MONSANTO COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4008281-A | BIS-PHOSPHINE | MONSANTO COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255391-A1 | Chiral Phosphorus Compounds | PHOSPHO1, PNKP, PTMS | KMT2A 3836/4885MEN1 3668/4885L3MBTL1 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.