Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396406 | 0.86 | KMT2A (0.73) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL24308948 | 0.86 | KMT2A (0.79) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL3807805 | 0.86 | KMT2A (0.73) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL28685764 | 0.86 | KMT2A (0.73) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL15715568 | 0.85 | MEN1 (0.56) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL23658968 | 0.80 | KMT2A (0.64) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL23658897 | 0.80 | KMT2A (0.64) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL15715690 | 0.79 | MEN1 (0.50) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL6828371 | 0.77 | KMT2A (0.61) | KMT2AMEN1HTTL3MBTL1POLB | |
| SCHEMBL23658965 | 0.77 | KMT2A (0.60) | KMT2AMEN1HTTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920189-B1 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-8816112-B2 | Process for making novel chiral phosphorus ligands | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| WO-2014078491-A1 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-22 | — | — | WO | disclosed |
| US-20140135506-A1 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135506-A1 | PROCESS FOR MAKING NOVEL CHIRAL PHOSPHORUS LIGANDS | PHOSPHO1, INPP5B, PLCG2 | KMT2A 3508/4885MEN1 1250/4885HTT 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.