Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 17/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380424 | 0.93 | CHRM2 (0.50) | CHRM2CHRM3 | |
| SCHEMBL380442 | 0.92 | CHRM2 (0.51) | SLC2A1CHRM2CHRM3 | |
| SCHEMBL381015 | 0.92 | SLC2A1 (0.56) | SLC2A1CHRM3ADRB2 | |
| SCHEMBL380349 | 0.91 | SLC2A1 (0.49) | SLC2A1CHRM2CHRM3ADRB2 | |
| SCHEMBL380992 | 0.89 | CHRM2 (0.60) | SLC2A1CHRM2CHRM3 | |
| SCHEMBL381053 | 0.88 | CHRM2 (0.60) | SLC2A1CHRM2CHRM3 | |
| SCHEMBL783823 | 0.86 | CHRM3 (0.51) | CHRM2CHRM3 | |
| SCHEMBL380326 | 0.86 | CHRM3 (0.64) | CHRM3 | |
| SCHEMBL783791 | 0.86 | CHRM2 (0.50) | SLC2A1CHRM2CHRM3 | |
| SCHEMBL381424 | 0.85 | CHRM2 (0.54) | SLC2A1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| EP-2409977-A1 | AMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-01-25 | — | — | EP | disclosed |