Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 20/20 | 0.51 |
| ▸ | ESR1 | P03372 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809431 | 0.82 | ESR2 (0.53) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL9294372 | 0.80 | ADRA2A (0.33) | ESR2ESR1 | |
| SCHEMBL29636477 | 0.77 | CYP1A2 (0.54) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL3815663 | 0.76 | ESR2 (0.54) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL2951103 | 0.75 | ESR2 (0.61) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3809870 | 0.74 | ESR2 (0.51) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3809761 | 0.74 | ESR2 (0.51) | ESR2ESR1CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL3817468 | 0.74 | ESR2 (0.51) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL3807888 | 0.73 | ESR2 (0.50) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL3811845 | 0.73 | ESR2 (0.50) | ESR2ESR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375461-B1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | HONSHU CHEMICAL IND (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6872858-B2 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040049086-A1 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1375461-A1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | Honshu Chemical Industry Co. Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049086-A1 | Diphenol and process for producing the same | CYP1A1, AHR, CYP2E1 | ESR2 940/4885ESR1 489/4885CYP3A4 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.