Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814666 | 0.89 | TRIM24 (0.47) | KDM4E | |
| SCHEMBL3816632 | 0.89 | NPSR1 (0.49) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL3811604 | 0.88 | NPSR1 (0.41) | KDM4E | |
| SCHEMBL2157876 | 0.87 | MEN1 (0.56) | MEN1KMT2AMAPTPOLBTP53 | |
| SCHEMBL3812602 | 0.87 | NPSR1 (0.46) | KDM4E | |
| SCHEMBL3811170 | 0.86 | PTGES2 (0.42) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL3811426 | 0.86 | RAD52 (0.47) | MEN1KMT2AGAAHTTALDH1A1 | |
| SCHEMBL3815294 | 0.86 | NPSR1 (0.42) | KDM4E | |
| SCHEMBL3816724 | 0.86 | ACLY (0.47) | — | |
| SCHEMBL3807312 | 0.86 | NPSR1 (0.53) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |