Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | IDH1 | O75874 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816632 | 0.90 | NPSR1 (0.49) | HTTNPSR1 | |
| SCHEMBL3807312 | 0.89 | NPSR1 (0.53) | ACLYNPSR1 | |
| SCHEMBL3817350 | 0.88 | IDH1 (0.48) | MCL1IDH1NPSR1PTGES2 | |
| SCHEMBL3812602 | 0.88 | NPSR1 (0.46) | ACLYNPSR1 | |
| SCHEMBL3815089 | 0.87 | NPSR1 (0.44) | MCL1POLBNPSR1 | |
| SCHEMBL3807338 | 0.87 | ACLY (0.44) | MCL1ACLYNPSR1 | |
| SCHEMBL3815294 | 0.87 | NPSR1 (0.42) | ACLYNPSR1 | |
| SCHEMBL3816724 | 0.87 | ACLY (0.47) | IDH1ACLYNPSR1PTGES2 | |
| SCHEMBL3812782 | 0.87 | NPSR1 (0.47) | MCL1HTTNPSR1 | |
| SCHEMBL3811426 | 0.87 | RAD52 (0.47) | HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |