Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809674 | 0.92 | CHRM1 (0.43) | SLC6A2SLC6A4SLC6A3PDK1CHRM1 | |
| SCHEMBL2157718 | 0.86 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3PDK1CHRM1 | |
| SCHEMBL2157539 | 0.78 | CHRM1 (0.43) | SLC6A2SLC6A4SLC6A3PDK1CHRM1 | |
| SCHEMBL3809712 | 0.77 | POLB (0.50) | TP53 | |
| SCHEMBL3807319 | 0.76 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3CHRM1CHEK1 | |
| SCHEMBL2876885 | 0.76 | CYP3A4 (0.39) | TP53 | |
| SCHEMBL3807275 | 0.75 | CPB1 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3809158 | 0.74 | POLB (0.39) | TP53 | |
| SCHEMBL3809118 | 0.74 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CHRM1CHEK1 | |
| SCHEMBL3817103 | 0.74 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CHRM1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |