SCHEMBL38112

SCHEMBL38112

CC(C)(C)OC(=O)CC(N)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 8/20 0.47
SLC7A5 Q01650 2/20 0.45
GRIK2 Q13002 4/20 0.44
GRM1 Q13255 1/20 0.42
GRM2 Q14416 1/20 0.42
GRIA4 P48058 3/20 0.41
GRIK3 Q13003 3/20 0.41
GRIK5 Q16478 3/20 0.41
CYP2D6 P10635 1/20 0.41
SLC1A1 P43005 4/20 0.41
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
GRIA2 P42262 2/20 0.40
GRIA1 P42261 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38111 1.00 GRIK1 (0.47) GRIK1SLC7A5GRIK2GRM1GRM2
SCHEMBL2024581 1.00 GRIK1 (0.47) GRIK1SLC7A5GRIK2GRM1GRM2
SCHEMBL28097905 0.98 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
Hydrochloric Acid SCHEMBL6361420 0.98 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
Methane SCHEMBL15302692 0.98 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
SCHEMBL28097904 0.98 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
Methane SCHEMBL15302681 0.98 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
Water SCHEMBL27830506 0.98 GRIK1 (0.46) GRIK1SLC7A5GRIK2GRM1GRM2
SCHEMBL8149690 0.87 SLC7A5 (0.47) GRIK1SLC7A5GRIK2GRIA4GRIK3
SCHEMBL3600281 0.87 SLC7A5 (0.47) GRIK1SLC7A5GRIK2GRIA4GRIK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350450-A Water-based synthesis method of mu-conotoxin KIIIA with instant wrinkle removal effect 润辉生物技术(威海)有限公司 2025-01-24 CN claimed
CN-117777248-A Water-based solid phase synthesis method of multi-receptor agonist polypeptide Retatrutide 润辉生物技术(威海)有限公司 2024-03-29 CN claimed
CN-117024316-A 2, 4-binitro-6-phenyl-phenylthio protecting group and polypeptide synthesis method thereof 南开大学 2023-11-10 CN claimed
CN-107473978-B Curcumin derivative and preparation method and application thereof GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) 2019-12-10 CN claimed
CN-106045883-B A kind of preparation method of aspartic acid -1- tert-butyl ester derivatives 成都郑源生化科技有限公司 2018-06-22 CN claimed
CN-1450999-A Novel piperazine derivatives PFIZER PROD INC (US) 2003-10-22 CN claimed
WO-2026099867-A1 SUSTAINABLE ANTIFREEZE COATINGS BY PEPTIDE SELF-ASSEMBLY YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2026-05-15 WO disclosed
US-12605451-B2 Targeted plasma protein degradation NOVARTIS AG (CH) 2026-04-21 US disclosed
US-20250367300-A1 Nanomaterial and Methods of Use Thereof UNIVERSITY OF CONNECTICUT (US) 2025-12-04 US disclosed
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
EP-4504732-A2 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF University of Connecticut (US) 2025-02-12 EP disclosed
US-12209144-B2 Cyclic peptides as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders NOVARTIS AG (CH) 2025-01-28 US disclosed
CN-119350450-A Water-based synthesis method of mu-conotoxin KIIIA with instant wrinkle removal effect 润辉生物技术(威海)有限公司 2025-01-24 CN disclosed
CN-1111630-A Adhesion receptor antagonists MERCK PATENT GMBH (DE) 1995-11-15 CN disclosed
EP-0301751-B1 PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1993-03-10 EP disclosed
US-4962113-A PLATELET ACTIVATING FACTOR ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD (JP) 1990-10-09 US disclosed
EP-0301751-A1 Pyridinium derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-01 EP disclosed
EP-0082712-B1 2-PHENYLIMIDAZO(2,1-B)BENZOTHIAZOLE COMPOUNDS, SALTS THEREOF, PROCESS FOR PRODUCING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1987-06-16 EP disclosed
US-4464384-A SUPPRESSANTS OF IMMUNE RESPONSE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1984-08-07 US disclosed
EP-0082712-A2 2-Phenylimidazo(2,1-b)benzothiazole compounds, salts thereof, process for producing them, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1983-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367300-A1 Nanomaterial and Methods of Use Thereof EPCAM, CD47, JAK2 GRIK1 3939/4885SLC7A5 1405/4885GRIK2 4289/4885
US-12605451-B2 Targeted plasma protein degradation M6PR, ASGR1, IGF2R GRIK1 4488/4885SLC7A5 445/4885GRIK2 4417/4885
US-12209144-B2 Cyclic peptides as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders PCSK9, PCSK7, PCSK6 GRIK1 3042/4885SLC7A5 2930/4885GRIK2 4258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.