Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154782 | 0.90 | L3MBTL1 (0.70) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL20299180 | 0.90 | L3MBTL1 (0.79) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL20500014 | 0.90 | L3MBTL1 (0.74) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL30288350 | 0.89 | L3MBTL1 (0.77) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL16858391 | 0.89 | L3MBTL1 (0.65) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL9272300 | 0.89 | L3MBTL1 (0.81) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL4837972 | 0.89 | L3MBTL1 (0.77) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL30829569 | 0.88 | L3MBTL1 (0.64) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL6331080 | 0.88 | L3MBTL1 (0.71) | L3MBTL1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL30829561 | 0.88 | L3MBTL1 (0.64) | L3MBTL1MAPTSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B8 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-08-12 | — | — | EP | disclosed |
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |
| EP-1885695-A2 | NOVEL INDOLINE COMPOUNDS | LABORATOIRES FOURNIER S.A. (FR) | 2008-02-13 | — | — | EP | disclosed |
| WO-2007000550-A2 | NOVEL INDOLINE COMPOUNDS | LABORATOIRES FOURNIER S.A. (FR) | 2007-01-04 | — | — | WO | disclosed |