Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809821 | 0.88 | CYP11B1 (0.35) | ACLYGPR27MAPTTP53 | |
| SCHEMBL3809158 | 0.86 | POLB (0.39) | MAPTHPGDMEN1ALDH1A1GAA | |
| SCHEMBL2157936 | 0.86 | MAPT (0.38) | ACLYMAPTMEN1KMT2AKDM4E | |
| SCHEMBL3809084 | 0.84 | CYP1A2 (0.39) | MAPTHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL3814669 | 0.82 | NTRK1 (0.43) | GPR27HPGDALDH1A1GAANPSR1 | |
| SCHEMBL3816830 | 0.81 | MAPT (0.35) | MAPT | |
| SCHEMBL3816598 | 0.81 | MAPT (0.35) | MAPTHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL3811259 | 0.80 | KDM4E (0.43) | MAPTALDH1A1NPSR1KDM4ETP53 | |
| SCHEMBL3809443 | 0.80 | HTR2C (0.41) | MAPTNPC1RAB9ANPSR1KDM4E | |
| SCHEMBL3812631 | 0.80 | ACLY (0.41) | ACLYMAPTHPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |