Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809084 | 0.90 | CYP1A2 (0.39) | MAPTALDH1A1HPGD | |
| SCHEMBL3816830 | 0.89 | MAPT (0.35) | MAPT | |
| SCHEMBL3812533 | 0.89 | MAPT (0.38) | MAPTTP53MEN1ALDH1A1GAA | |
| SCHEMBL3816598 | 0.89 | MAPT (0.35) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL3809821 | 0.88 | CYP11B1 (0.35) | MAPTGPR27TP53ACLY | |
| SCHEMBL3807320 | 0.88 | MAPT (0.37) | MAPTTP53ACLYMEN1ALDH1A1 | |
| SCHEMBL3809457 | 0.88 | MAPT (0.38) | MAPTMEN1ALDH1A1GAAHPGD | |
| SCHEMBL3812104 | 0.87 | ACLY (0.39) | MAPTTP53ACLYMEN1ALDH1A1 | |
| SCHEMBL3807407 | 0.86 | IKBKB (0.36) | MAPT | |
| SCHEMBL2157883 | 0.86 | MAPT (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |