SCHEMBL3812227

SCHEMBL3812227

[CH2]CCCS(=O)(=O)Nc1ccc(C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.48
▸ CA2 P00918 3/20 0.48
▸ HPGD P15428 5/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ CA12 O43570 2/20 0.45
▸ CA9 Q16790 2/20 0.45
▸ CA4 P22748 1/20 0.45
▸ CA7 P43166 1/20 0.45
▸ LMNA P02545 3/20 0.44
▸ ALDH1A1 P00352 6/20 0.43
▸ MAPT P10636 3/20 0.43
▸ GAA P10253 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ HTT P42858 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ AR P10275 1/20 0.41
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482755 0.89 CA1 (0.52) CA1CA2HPGDMEN1KMT2A
SCHEMBL10192137 0.84 HPGD (0.60) CA1CA2HPGDMEN1KMT2A
SCHEMBL10191922 0.82 CA1 (0.48) CA1CA2HPGDMEN1KMT2A
SCHEMBL14509043 0.82 CA1 (0.48) CA1CA2HPGDMEN1KMT2A
SCHEMBL9453329 0.81 HPGD (0.56) CA1CA2HPGDMEN1KMT2A
SCHEMBL13763467 0.81 HPGD (0.56) CA1CA2HPGDMEN1KMT2A
SCHEMBL26277471 0.81 HPGD (0.56) CA1CA2HPGDMEN1KMT2A
SCHEMBL580978 0.81 CA1 (0.47) CA1CA2HPGDMEN1KMT2A
SCHEMBL11066198 0.81 HPGD (0.56) CA1CA2HPGDMEN1KMT2A
SCHEMBL10191923 0.79 CA1 (0.53) CA1CA2HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1872943-B1 Photosensitive composition and planographic printing plate base using same FUJIFILM CORP (JP) 2009-08-12 — — EP disclosed
EP-1053868-B1 Photosensitive composition and planographic printing plate base using same FUJIFILM CORP (JP) 2008-02-06 — — EP disclosed
EP-1872943-A2 Photosensitive composition and planographic printing plate base using same FUJIFILM Corporation (JP) 2008-01-02 — — EP disclosed
EP-1059164-B1 Image recording material and planographic printing plate using same FUJI PHOTO FILM CO LTD (JP) 2006-04-19 — — EP disclosed
EP-0945264-B1 Anionic infrared-ray absorbing agent, photosensitive composition and planographic printing plate precursor using same FUJI PHOTO FILM CO LTD (JP) 2003-09-24 — — EP disclosed
US-6602645-B1 Macromolecular compound having alkali soluble groups and metal phthalocyanine; high sensitivity; good developing latitude; storage stability; direct positive-type FUJI PHOTO FILM CO., LTD. (JP) 2003-08-05 — — US disclosed
US-6444393-B2 AN ANIONIC INFRARED ABSORBING AGENT AND A POLYMERIC COMPOUND THAT IS WATER INSOLUBLE BUT SOLUBLE IN AQUEOUS ALKALINE SOLUTION WHEN IRRADIATED WITH RADIATION FUJI PHOTO FILM CO., LTD. (JP) 2002-09-03 — — US disclosed
US-6383714-B1 COMPOUNDS DECOMPOSABLE BY LIGHT AND HEAT, CROSSLINKING, INFRARED ABSORBERS FUJI PHOTO FILM CO., LTD. (JP) 2002-05-07 — — US disclosed
US-20010003639-A1 An anionic infrared absorbing agent and a polymeric compound that is water insoluble but soluble in aqueous alkaline solution when irradiated with radiation TATSUO NAKAMURA 2001-06-14 — — US disclosed
EP-1059164-A2 Image recording material and planographic printing plate using same FUJI PHOTO FILM CO., LTD. (JP) 2000-12-13 — — EP disclosed
EP-0822447-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 2000-10-11 — — EP disclosed
EP-0726498-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1999-12-15 — — EP disclosed
EP-0945264-A1 Anionic infrared-ray absorbing agent, photosensitive composition and planographic printing plate precursor using same FUJI PHOTO FILM CO., LTD. (JP) 1999-09-29 — — EP disclosed
US-5939465-A COMPRISING N-HETEROCYCLE COMPOUND, COMPOUND CONTAINING AT LEAST ONE ADDITION-POLYMERIZABLE, ETHYLENICALLY UNSATURATED BOND, AND COMPOUND WHICH GENERATES AN ACTIVE RADICAL UPON IRRADIATION OF LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1999-08-17 — — US disclosed
US-5837748-A THIAZOLYLIDENE DERIVATIVE PHOTOINITIATOR; VISIBLE LIGHT PHOTOSENSITIVITY; PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1998-11-17 — — US disclosed
EP-0710887-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1998-07-29 — — EP disclosed
EP-0822447-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1998-02-04 — — EP disclosed
US-5609992-A UNSATURATED COMPOUND AND A THIAZOLONE PHOTOSENSITIZER FUJI PHOTO FILM CO., LTD. (JP) 1997-03-11 — — US disclosed
EP-0726498-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1996-08-14 — — EP disclosed
EP-0710887-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1996-05-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010003639-A1 An anionic infrared absorbing agent and a polymeric compound that is water insoluble but soluble in aqueous alkaline solution when irradiated with radiation GANAB, GNA11, GLA CA1 254/4885CA2 99/4885HPGD 3993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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