Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816881 | 0.87 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL2158136 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10KDM4EPOLB | |
| SCHEMBL2158138 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10KDM4EPOLB | |
| SCHEMBL3812581 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL3812630 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL3816838 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL3810022 | 0.85 | MEN1 (0.48) | ALDH1A1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL3809030 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10KDM4EPOLB | |
| SCHEMBL3808147 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10KDM4EL3MBTL1 | |
| SCHEMBL3807592 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |