Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.34 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810178 | 0.94 | SIGMAR1 (0.49) | SIGMAR1CYP2A6KDM4EOPRM1OPRK1 | |
| SCHEMBL14492178 | 0.88 | SIGMAR1 (0.53) | SIGMAR1CYP2A6KDM4EOPRM1OPRK1 | |
| Oxalic Acid SCHEMBL3812890 | 0.88 | SIGMAR1 (0.48) | SIGMAR1CYP2A6 | |
| SCHEMBL3817737 | 0.88 | SIGMAR1 (0.53) | SIGMAR1CYP2A6CTNNB1WNT3AMRGPRX4 | |
| Oxalic Acid SCHEMBL3816423 | 0.88 | SIGMAR1 (0.45) | SIGMAR1CTNNB1WNT3AMRGPRX4ALDH1A1 | |
| Oxalic Acid SCHEMBL3817540 | 0.87 | SIGMAR1 (0.52) | SIGMAR1CYP2A6KDM4ECTNNB1WNT3A | |
| Oxalic Acid SCHEMBL3807582 | 0.87 | SIGMAR1 (0.48) | SIGMAR1CYP2A6KDM4ECTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL3818441 | 0.86 | SIGMAR1 (0.52) | SIGMAR1CYP2A6KDM4ECTNNB1WNT3A | |
| SCHEMBL3807907 | 0.86 | SIGMAR1 (0.51) | SIGMAR1CYP2A6KDM4ECYP1A2CYP2D6 | |
| Oxalic Acid SCHEMBL3813198 | 0.86 | SIGMAR1 (0.48) | SIGMAR1CYP2A6KDM4ECTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |