Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426855 | 0.89 | SMN1; SMN2 (0.45) | CYP2E1HTTCYP2C19SMN1; SMN2 | |
| SCHEMBL2876357 | 0.84 | CYP2E1 (0.42) | CYP2E1KDM4EHTTATMNR1I2 | |
| SCHEMBL2157834 | 0.83 | CYP2E1 (0.43) | CYP2E1KDM4EHTTATMPKM | |
| Hydrochloric Acid SCHEMBL2874873 | 0.83 | CYP2E1 (0.41) | CYP2E1KDM4EHTTATMNR1I2 | |
| SCHEMBL14030873 | 0.83 | SMN1; SMN2 (0.43) | HTTCYP2C19SMN1; SMN2 | |
| SCHEMBL12464666 | 0.83 | SMN1; SMN2 (0.45) | HTTCYP2C19SMN1; SMN2 | |
| SCHEMBL3811676 | 0.82 | SLC6A12 (0.35) | — | |
| SCHEMBL2879579 | 0.82 | SMN1; SMN2 (0.44) | KDM4EHTTATMCYP2C19SMN1; SMN2 | |
| SCHEMBL2879394 | 0.81 | KDM4E (0.42) | KDM4EHTTATMSMN1; SMN2 | |
| SCHEMBL3812854 | 0.80 | CHRM1 (0.39) | CYP2E1KDM4EHTTATMNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |