SCHEMBL3812804

SCHEMBL3812804

CCC(C)COc1ccc(C2(c3ccc(OCC(C)CC)cc3)c3ccccc3-c3ccc(Br)cc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.40
FFAR1 O14842 1/20 0.39
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GPR88 Q9GZN0 4/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
GPBAR1 Q8TDU6 1/20 0.34
TLR8 Q9NR97 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3817804 0.98 PDK2 (0.38) PDK2FFAR1KDM4EMEN1LMNA
SCHEMBL13615383 0.86 PDK2 (0.40) PDK2FFAR1KDM4EMEN1LMNA
SCHEMBL13607197 0.83 PDK2 (0.35) PDK2FFAR1GPR88
SCHEMBL30673176 0.83 PDK2 (0.49) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL5652886 0.80 TLR8 (0.32) PDK2TLR8
SCHEMBL13607212 0.80 FFAR1 (0.39) PDK2FFAR1GPR88GPBAR1
SCHEMBL21793375 0.80 MEN1 (0.39) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL29523937 0.80 MEN1 (0.39) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL13816600 0.80 TLR8 (0.34) TLR8
SCHEMBL29127144 0.79 GPR88 (0.42) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615289-B2 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK ENERGY CO., LTD. (KR) 2009-11-10 US disclosed
US-7615289-B2 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK ENERGY CO., LTD. (KR) 2009-11-10 US disclosed
US-7615289-B2 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK ENERGY CO., LTD. (KR) 2009-11-10 US disclosed
US-20070093643-A1 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK CORPORATION (KR) 2007-04-26 US disclosed
US-20070093643-A1 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK CORPORATION (KR) 2007-04-26 US disclosed
US-20070093643-A1 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK CORPORATION (KR) 2007-04-26 US disclosed
EP-1709140-A1 ORGANIC ELECTROLUMINESCENT POLYMER HAVING 9,9-DI(FLUORENYL)-2,7-FLUORENYL UNIT AND ORGANIC ELECTROLUMINESCENT DEVICE MANUFACTURED USING THE SAME SK Corporation (KR) 2006-10-11 EP disclosed
WO-2005073337-A1 ORGANIC ELECTROLUMINESCENT POLYMER HAVING 9,9-DI(FLUORENYL)-2,7-FLUORENYL UNIT AND ORGANIC ELECTROLUMINESCENT DEVICE MANUFACTURED USING THE SAME SK CORPORATION (KR) 2005-08-11 WO disclosed