Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 7/20 | 1.00 |
| ▸ | SLC5A2 | P31639 | 7/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | SLC16A3 | O15427 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phloretin SCHEMBL1506325 | 1.00 | SLC5A1 (1.00) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL31684375 | 0.98 | SLC5A1 (0.96) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL30912872 | 0.98 | SLC5A1 (0.96) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL30785809 | 0.98 | SLC5A1 (0.96) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL27910960 | 0.96 | SLC5A1 (0.93) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL28362318 | 0.93 | SLC5A1 (0.87) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL30603791 | 0.93 | SLC5A1 (0.87) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL21192491 | 0.93 | SLC5A1 (0.87) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL6402644 | 0.93 | SLC5A1 (0.87) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 | |
| Phloretin SCHEMBL27906064 | 0.93 | SLC5A1 (0.87) | SLC5A1SLC5A2CYP19A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9048 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747367-A1 | NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES | Symrise AG (DE) | 2026-05-27 | — | — | EP | claimed |
| CN-122074552-A | Liquid preservative for preserving fresh walnut kernels | — | 2026-05-26 | — | — | CN | claimed |
| CN-122031436-A | Application of phloretin in preparation of medicament for improving muscular atrophy | 南京大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122031336-A | Whitening and freckle-removing composition based on multi-channel synergy and application thereof | 广州诺彦生物科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122012432-A | Phloretin enzyme activity related protein, and coding gene and application thereof | 中国中医科学院中药研究所 | 2026-05-12 | — | — | CN | claimed |
| US-20260069523-A1 | SKIN CARE COMPOSITION AND USE THEREOF | NANJING NUTRABUILDING BIO TECH CO LTD (CN) | 2026-03-12 | — | — | US | claimed |
| EP-4704600-A1 | DAIRY BEVERAGES WITH IMPROVED TASTE | The Coca-Cola Company (US) | 2026-03-11 | — | — | EP | claimed |
| EP-4704601-A1 | DAIRY-ALTERNATIVE BEVERAGES WITH IMPROVED TASTE | The Coca-Cola Company (US) | 2026-03-11 | — | — | EP | claimed |
| EP-4701427-A1 | THERMAL ENERGY SYSTEM FOR ADMINISTERING ACTIVE AGENTS | UltraOral Ltd. (IL) | 2026-03-04 | — | — | EP | claimed |
| US-20260048027-A1 | METHYLATED PHLORETIN ANALOGS AS INHIBITORS OF SGLT2 | NESTLE SA (CH) | 2026-02-19 | — | — | US | claimed |
| WO-1992006685-A1 | ENHANCEMENT OF CELLULAR ACCUMULATION OF LIPOPHILIC CATIONIC ORGANOMETALLIC COMPOUNDS BY REDUCTION OF INTRAMEMBRANE POTENTIAL | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1992-04-30 | — | — | WO | claimed |
| EP-0445255-A1 | TREATMENT OF CONDITIONS AND DISEASE. | NORPHARMCO INC (CA) | 1991-09-11 | — | — | EP | claimed |
| CN-1051503-A | Disease and treatment of diseases | NORPHARMCO INC (CA) | 1991-05-22 | — | — | CN | claimed |
| WO-1991004058-A2 | TREATMENT OF CONDITIONS AND DISEASE | NORPHARMCO INC. (CA) | 1991-04-04 | — | — | WO | claimed |
| US-4959355-A | GLUCOSE TRANSPORT BLOCKER | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1990-09-25 | — | — | US | claimed |
| US-4840939-A | Treatment of cancer with phlorizin and its derivatives | LEVEEN HARRY H (US) | 1989-06-20 | — | — | US | claimed |
| EP-0292576-A1 | ANTI-ULCEROUS AGENT CONTAINING CHALCONE DERIVATIVE AS EFFECTIVE INGREDIENT AND NOVEL CHALCONE DERIVATIVES | TSUMURA & CO. (JP) | 1988-11-30 | — | — | EP | claimed |
| EP-0291151-A1 | Compositions comprising phlorizin derivatives for treatment of cancer | Leveen, Harry H. (US) | 1988-11-17 | — | — | EP | claimed |
| US-4219569-A | CARBOCYCLIC KETONES | THE UPJOHN COMPANY (US) | 1980-08-26 | — | — | US | claimed |
| US-3977944-A | Enzyme-kinetic determination of the concentration of a substrate | EPPENDORF GERATEBAU NETHELER & HINZ GMBH (DT) | 1976-08-31 | — | — | US | claimed |