Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350254 | 1.00 | EPHX1 (0.31) | EPHX1GAAPKMTDP1CYP1A2 | |
| SCHEMBL5709 | 1.00 | EPHX1 (0.31) | EPHX1GAAPKMTDP1CYP1A2 | |
| SCHEMBL5118 | 1.00 | EPHX1 (0.31) | EPHX1GAAPKMTDP1CYP1A2 | |
| SCHEMBL5022 | 0.97 | — | — | |
| SCHEMBL5689 | 0.90 | — | — | |
| SCHEMBL349126 | 0.83 | — | — | |
| SCHEMBL28746805 | 0.77 | EPHX1 (0.33) | EPHX1SSTR4 | |
| SCHEMBL879449 | 0.75 | LMNA (0.38) | EPHX1GAAPKMTDP1CYP1A2 | |
| SCHEMBL9897847 | 0.75 | LMNA (0.38) | EPHX1GAAPKMTDP1CYP1A2 | |
| SCHEMBL8502985 | 0.75 | LMNA (0.38) | EPHX1GAAPKMTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089373-A1 | STAT3/5 ACTIVATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-08-19 | — | — | EP | disclosed |
| EP-1957073-A2 | MEDICINAL DRUG | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2008044667-A1 | STAT3/5 ACTIVATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | WO | disclosed |
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |