Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 11/20 | 0.55 |
| ▸ | BIRC3 | Q13489 | 9/20 | 0.55 |
| ▸ | CASP9 | P55211 | 1/20 | 0.54 |
| ▸ | BIRC2 | Q13490 | 16/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810557 | 0.93 | XIAP (0.59) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL3813030 | 0.90 | XIAP (0.60) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL3813915 | 0.89 | XIAP (0.55) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL3812135 | 0.87 | XIAP (0.56) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL12467179 | 0.87 | XIAP (0.56) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL3813690 | 0.87 | XIAP (0.53) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL3820356 | 0.87 | XIAP (0.59) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL12465437 | 0.86 | XIAP (0.55) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL3810572 | 0.86 | XIAP (0.55) | XIAPBIRC3CASP9BIRC2 | |
| SCHEMBL3824429 | 0.85 | XIAP (0.57) | XIAPBIRC3CASP9BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874748-B1 | 2 -AMINOCARBONYL SUBSTITUTED PIPERAZINE OR DIAZA-CYCLIC COMPOUNDS AS APOPTOSIS PROTEIN INHIBITOR (IAP) MODULATORS | NOVARTIS AG (CH) | 2009-08-12 | — | — | EP | claimed |
| EP-1874748-B1 | 2 -AMINOCARBONYL SUBSTITUTED PIPERAZINE OR DIAZA-CYCLIC COMPOUNDS AS APOPTOSIS PROTEIN INHIBITOR (IAP) MODULATORS | NOVARTIS AG (CH) | 2009-08-12 | — | — | EP | disclosed |