SCHEMBL3813974

SCHEMBL3813974

NC(=O)C(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL27867613 0.89 PKM (0.34)
SCHEMBL8385684 0.77
SCHEMBL839714 0.77
SCHEMBL29233420 0.75 PKM (0.30)
SCHEMBL27837865 0.75 PKM (0.35)
SCHEMBL865265 0.73
SCHEMBL11674335 0.73 PKM (0.42)
SCHEMBL31272405 0.73
SCHEMBL322006 0.73
SCHEMBL13104173 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102431-A Preparation method and application of ishikawa reagent 常州齐晖药业有限公司 2023-05-12 CN claimed
CN-103508875-A 2,3,3,3-tetrafluoro propionic acid (I) synthesis method ZHAO LEI 2014-01-15 CN claimed
CN-103254058-A Process for synthesizing 2, 3, 3, 3-tetrafluoropropionic acid JINGSHAN RUISHENG PHARMACEUTICAL CO LTD 2013-08-21 CN claimed
CN-102639516-A 3-amino-5-phenyl-5, 6-dihydro-2H- [1,4] oxazine derivatives HOFFMANN LA ROCHE 2012-08-15 CN claimed
US-20090264499-A1 Cathepsin C Inhibitors GLAXO GROUP LIMITED (GB) 2009-10-22 US claimed
WO-2009129371-A1 CATHEPSIN C INHIBITORS GLAXO GROUP LIMITED (GB) 2009-10-22 WO claimed
EP-1702963-A1 Anti-moisture and soil-repellent coatings JDS Uniphase Corporation (US) 2006-09-20 EP claimed
US-20250320192-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2025-10-16 US disclosed
EP-3951444-B1 OPTICAL DEVICE HAVING OPTICAL AND MECHANICAL PROPERTIES VIAVI SOLUTIONS INC (US) 2025-10-01 EP disclosed
US-20250123425-A1 OPTICAL DEVICE HAVING OPTICAL AND MECHANICAL PROPERTIES VIAVI SOLUTIONS INC. (US) 2025-04-17 US disclosed
US-12174342-B2 Optical device having optical and mechanical properties VIAVI SOLUTIONS INC. (US) 2024-12-24 US disclosed
EP-3827241-B1 DISSOCIATION OF BIOLOGICAL SAMPLES GOLDSBOROUGH ANDREW SIMON (FR) 2024-03-13 EP disclosed
US-20230242504-A1 DEUTERIUM-ENRICHED PIPERIDINONYL-OXOISOINDOLINYL ACETAMIDES AND METHODS OF TREATING MEDICAL DISORDERS USING SAME DEUTERX LLC (US) 2023-08-03 US disclosed
WO-2009129371-A1 CATHEPSIN C INHIBITORS GLAXO GROUP LIMITED (GB) 2009-10-22 WO disclosed
CN-1839120-A Process for producing cis-4-fluoro-L-proline derivative TAISHO PHARMACEUTICAL CO LTD (JP) 2006-09-27 CN disclosed
EP-1702963-A1 Anti-moisture and soil-repellent coatings JDS Uniphase Corporation (US) 2006-09-20 EP disclosed
US-6710060-B2 4-hydroxypiperidine derivatives having antiarrhythmic activity MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2004-03-23 US disclosed
US-20020188006-A1 4-hydroxypiperidine derivatives having antiarrhythmic activity MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2002-12-12 US disclosed
EP-1182192-A1 4-HYDROXYPIPERIDINE DERIVATIVES HAVING ANTIARRHYTHMIC EFFECT MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2002-02-27 EP disclosed
CN-1323784-A Amidine compound and usage as insecticide SUMITOMO CHEMICAL CO (JP) 2001-11-28 CN disclosed