Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 9/20 | 1.00 |
| ▸ | ITPR1 | Q14643 | 5/20 | 1.00 |
| ▸ | ITPR2 | Q14571 | 4/20 | 1.00 |
| ▸ | INPP5A | Q14642 | 2/20 | 1.00 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.90 |
| ▸ | AKT1 | P31749 | 1/20 | 0.90 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ins(1,4,5)P3 SCHEMBL9383914 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL4871682 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL28087353 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL9382320 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL98182 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL10490812 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL4321735 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL382820 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| Ins(1,4,5)P3 SCHEMBL4874594 | 1.00 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL19532798 | 0.94 | ITPR3 (1.00) | ITPR3ITPR1ITPR2INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408481-A2 | MAGNETIC RESONANCE IMAGING CONTRAST AGENT WITH PARAMAGNETIC-INOSITOL PHOSPHATES COMPLEXES | Gachon University Of Medicine&Science Industry- Academic Cooperation Foundation (KR) | 2012-01-25 | — | — | EP | claimed |
| WO-2010107178-A2 | MAGNETIC RESONANCE IMAGING CONTRAST AGENT WITH PARAMAGNETIC-INOSITOL PHOSPHATES COMPLEXES | GACHON UNIVERSITY OF MEDICINE & SCIENCE INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2010-09-23 | — | — | WO | claimed |
| US-20100233093-A1 | Magnetic resonance imaging contrast agent with paramagnetic-inositol phosphates complexes | GACHON UNIVERSITY OF MEDICINE & SCIENCE INDUSTRY-ACADEMIC CORPERATION FOUNDATION (KR) | 2010-09-16 | — | — | US | claimed |
| US-4873355-A | Process for regioselectively preparing phosphorylated inositols and other cyclitols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-10 | — | — | US | claimed |
| EP-0262227-A1 | Process for the preparation of myoinositol derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-04-06 | — | — | EP | claimed |
| CN-109563056-B | Triazoles for modulating intracellular calcium homeostasis | 巴斯克大学 | 2022-08-16 | — | — | CN | disclosed |
| EP-3004394-A1 | ASSAYS, METHODS AND KITS FOR ANALYZING SENSITIVITY AND RESISTANCE TO ANTI-CANCER DRUGS, PREDICTING A CANCER PATIENT'S PROGNOSIS, AND PERSONALIZED TREATMENT STRATEGIES | University Of Miami (US) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014197543-A1 | ASSAYS, METHODS AND KITS FOR ANALYZING SENSITIVITY AND RESISTANCE TO ANTI-CANCER DRUGS, PREDICTING A CANCER PATIENT'S PROGNOSIS, AND PERSONALIZED TREATMENT STRATEGIES | UNIVERSITY OF MIAMI (US) | 2014-12-11 | — | — | WO | disclosed |
| EP-2408481-A2 | MAGNETIC RESONANCE IMAGING CONTRAST AGENT WITH PARAMAGNETIC-INOSITOL PHOSPHATES COMPLEXES | Gachon University Of Medicine&Science Industry- Academic Cooperation Foundation (KR) | 2012-01-25 | — | — | EP | disclosed |
| US-7989602-B2 | having biological activity similar to PIM (acyl glycerol phosphatidylinositol manno-oligosacccharide) activity; asthma, allergic rhinitis, dermatitis, psoriasis, inflammatory bowel disease including Crohn's disease and ulcerative colitis, rheumatoid arthritis, multiple sclerosis, diabetes, systemic lupus | THE MALAGHAN INSTITUTE OF MEDICAL RESEARCH (NZ) | 2011-08-02 | — | — | US | disclosed |
| WO-2010107178-A2 | MAGNETIC RESONANCE IMAGING CONTRAST AGENT WITH PARAMAGNETIC-INOSITOL PHOSPHATES COMPLEXES | GACHON UNIVERSITY OF MEDICINE & SCIENCE INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2010-09-23 | — | — | WO | disclosed |
| US-20100233093-A1 | Magnetic resonance imaging contrast agent with paramagnetic-inositol phosphates complexes | GACHON UNIVERSITY OF MEDICINE & SCIENCE INDUSTRY-ACADEMIC CORPERATION FOUNDATION (KR) | 2010-09-16 | — | — | US | disclosed |
| US-4924023-A | MEDICINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0354904-A1 | INOSITOL PHOSPHATE ANALOGUES | 3i RESEARCH EXPLOITATION LIMITED (GB) | 1990-02-21 | — | — | EP | disclosed |
| US-4873355-A | Process for regioselectively preparing phosphorylated inositols and other cyclitols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| US-4873355-A | Process for regioselectively preparing phosphorylated inositols and other cyclitols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| WO-1989000156-A1 | PREPARATION OF ISOMERS OF MYO-INOSITOL DERIVATIVES | 3I RESEARCH EXPLOITATION LIMITED (GB) | 1989-01-12 | — | — | WO | disclosed |
| WO-1988007047-A1 | INOSITOL PHOSPHATE ANALOGUES | RESEARCH CORPORATION LIMITED (GB) | 1988-09-22 | — | — | WO | disclosed |
| US-4755612-A | Intermediate compounds resulting from method for forming a dihydrogen-phosphate inositol | MERCK & CO., INC. (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0262227-A1 | Process for the preparation of myoinositol derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-04-06 | — | — | EP | disclosed |