SCHEMBL3814580

SCHEMBL3814580

CCCCC(CC)CC1(CC(CC)CCCC)c2cc(Cl)ccc2-c2ccc(Cl)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
MAPK1 P28482 1/20 0.40
PDK2 Q15119 1/20 0.35
CRHR1 P34998 5/20 0.35
PIM1 P11309 1/20 0.34
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP3A4 P08684 2/20 0.33
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32
PSENEN Q9NZ42 1/20 0.32
CA2 P00918 1/20 0.32
AKR1A1 P14550 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31388556 1.00 ALDH1A1 (0.40) ALDH1A1MAPK1PDK2CRHR1PIM1
SCHEMBL6018079 0.89 ALDH1A1 (0.36) ALDH1A1MAPK1PDK2TSHRCA2
SCHEMBL6018365 0.88 ALDH1A1 (0.34) ALDH1A1MAPK1PDK2
SCHEMBL6018141 0.88 ALDH1A1 (0.40) ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL5347840 0.82 ALDH1A1 (0.33) ALDH1A1MAPK1TSHRTDP1MEN1
SCHEMBL29539705 0.82 ALDH1A1 (0.33) ALDH1A1MAPK1PDK2TSHRTDP1
SCHEMBL6032873 0.82 ALDH1A1 (0.37) ALDH1A1MAPK1TSHRTDP1MEN1
SCHEMBL679081 0.82 ALDH1A1 (0.33) ALDH1A1MAPK1PDK2TSHRTDP1
SCHEMBL23723924 0.80 ALDH1A1 (0.33) ALDH1A1MAPK1TSHRTDP1MEN1
SCHEMBL30127573 0.80 ALDH1A1 (0.33) ALDH1A1MAPK1TSHRTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0842208-B2 2,7-ARYL-9-SUBSTITUTED FLUORENES AND 9-SUBSTITUTED FLUORENE OLIGOMERS AND POLYMERS SUMITOMO CHEMICAL CO (JP) 2009-08-19 EP disclosed
US-7138483-B2 Monomers, conjugated polymers and electronic devices using such polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2006-11-21 US disclosed
US-6900285-B2 Fluorene-containing polymers and compounds useful in the preparation thereof DOW GLOBAL TECHNOLOGIES INC. (US) 2005-05-31 US disclosed
US-20040192871-A1 Monomers, conjugated polymers and electronic devices using such polymers E. I. DU PONT DE NEMOURS AND COMPANY 2004-09-30 US disclosed
US-20030208032-A1 Fluorene-containing polymers and compounds useful in the preparation thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-11-06 US disclosed
US-6593450-B2 Aromatic resins; electronics; films DOW GLOBAL TECHNOLOGIES INC. 2003-07-15 US disclosed
US-6514632-B1 Electroluminescent films and coatings for light emitting diodes; efficiency DOW GLOBAL TECHNOLOGIES INC. 2003-02-04 US disclosed
US-6512083-B1 Film prepared from the polymers of this invention. this invention is a light-emitting diode comprised of one or more layers of polymer films, at least one of which is derived from the oligomers and polymers of the invention. DOW GLOBAL TECHNOLOGIES INC. 2003-01-28 US disclosed
US-6362310-B1 LIGHT EMITTING POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-26 US disclosed
US-20010053842-A1 2,7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-20 US disclosed
US-6255449-B1 PROCESS FOR PREPARING POLYMERS HAVING AT LEAST THREE FLUORENE GROUPS IN BACKBONE, WHICH COMPRISES HEATING 2,7-DIHALO-9-SUBSTITUTED FLUORENES UNDER REACTION CONDITIONS SUFFICIENT TO FORM SAID POLYMERS THE DOW CHEMICAL COMPANY 2001-07-03 US disclosed
US-6255447-B1 OLIGOMERS OR POLYMERS WHICH DEMONSTRATE FLUORESCENCE, HIGH GLASS TRANSITION TEMPERATURES OR LIQUID-CRYSTALLINE PROPERTIES; FACILITATE PREPARATION OF FILMS HAVING HIGH HEAT RESISTANCE AND SOLVENT RESISTANCE THE DOW CHEMICAL COMPANY 2001-07-03 US disclosed
US-6169163-B1 NOVEL 2,7-DIHALOFLUORENES SUBSTITUTED AT 9-POSITION THE DOW CHEMICAL COMPANY 2001-01-02 US disclosed
EP-0842208-B1 2,7-ARYL-9-SUBSTITUTED FLUORENES AND 9-SUBSTITUTED FLUORENE OLIGOMERS AND POLYMERS DOW CHEMICAL CO (US) 2000-05-17 EP disclosed
US-5962631-A 2, 7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers THE DOW CHEMICAL COMPANY (US) 1999-10-05 US disclosed
EP-0842208-A1 2,7-ARYL-9-SUBSTITUTED FLUORENES AND 9-SUBSTITUTED FLUORENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1998-05-20 EP disclosed
US-5708130-A 2,7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers THE DOW CHEMICAL COMPANY (US) 1998-01-13 US disclosed
WO-1997005184-A1 2,7-ARYL-9-SUBSTITUTED FLUORENES AND 9-SUBSTITUTED FLUORENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-02-13 WO disclosed