Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811287 | 0.95 | MEN1 (0.34) | MEN1KMT2ANPY1RUSP30 | |
| SCHEMBL3814854 | 0.95 | MEN1 (0.39) | MEN1KMT2ANPY1RUSP30GPR119 | |
| SCHEMBL3808918 | 0.93 | MEN1 (0.37) | MEN1KMT2ANPY1RUSP30GPR119 | |
| SCHEMBL6426599 | 0.88 | USP30 (0.47) | MEN1KMT2AUSP30MCHR1GPR119 | |
| SCHEMBL2158008 | 0.86 | MEN1 (0.52) | MEN1KMT2AUSP30GPR119 | |
| SCHEMBL6431276 | 0.85 | ACKR3 (0.43) | MEN1KMT2AUSP30GPR119 | |
| SCHEMBL6429324 | 0.83 | MEN1 (0.49) | MEN1KMT2AUSP30GPR119 | |
| SCHEMBL2158478 | 0.82 | MCHR1 (0.39) | NPY1RMCHR1 | |
| SCHEMBL2157663 | 0.82 | OPRM1 (0.41) | NPY1RMCHR1 | |
| SCHEMBL2157808 | 0.81 | CYP1A2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |