Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TNKS | O95271 | 6/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.51 |
| ▸ | GABRP | O00591 | 3/20 | 0.51 |
| ▸ | GABRD | O14764 | 3/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844010 | 0.83 | NPC1 (0.65) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL11497113 | 0.81 | NPC1 (0.68) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| Methane SCHEMBL11545753 | 0.77 | SMN1; SMN2 (0.58) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL2465240 | 0.77 | HPGD (1.00) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL435366 | 0.77 | HPGD (1.00) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL24241713 | 0.75 | KDM4E (0.63) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL8493846 | 0.75 | HPGD (0.63) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL10615084 | 0.73 | KDM4E (0.78) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL9976005 | 0.73 | KDM4E (0.78) | NPC1SMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL9975965 | 0.73 | KDM4E (0.78) | NPC1SMN1; SMN2RAB9AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740225-A4 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL MYERS SQUIBB CO (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1740225-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | Bristol-Myers Squibb Company (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105159-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-11-10 | — | — | WO | disclosed |