Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23460875 | 1.00 | CXCR2 (0.46) | CXCR2PPARDPPARALRRK2KIFC1 | |
| SCHEMBL23460874 | 1.00 | CXCR2 (0.46) | CXCR2PPARDPPARALRRK2KIFC1 | |
| SCHEMBL38146980 | 0.97 | CXCR2 (0.47) | CXCR2PPARDPPARALRRK2KIFC1 | |
| SCHEMBL23461018 | 0.97 | CXCR2 (0.47) | CXCR2PPARDPPARALRRK2KIFC1 | |
| SCHEMBL23460719 | 0.91 | CXCR2 (0.46) | CXCR2PPARDPPARALRRK2KIFC1 | |
| SCHEMBL38665689 | 0.91 | CXCR2 (0.46) | CXCR2PPARDPPARALRRK2KIFC1 | |
| SCHEMBL23460717 | 0.91 | CXCR2 (0.46) | CXCR2PPARDPPARALRRK2KIFC1 | |
| SCHEMBL23461461 | 0.90 | CXCR2 (0.37) | CXCR2PPARACNR1CNR2CYP3A4 | |
| SCHEMBL23461460 | 0.90 | CXCR2 (0.37) | CXCR2PPARACNR1CNR2CYP3A4 | |
| SCHEMBL38146994 | 0.90 | CXCR2 (0.37) | CXCR2PPARACNR1CNR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630498-B2 | Arylamides and methods of use thereof | GENZYME CORPORATION (US) | 2026-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630498-B2 | Arylamides and methods of use thereof | CFTR, CLIC1, CLCN2 | CXCR2 63/4885PPARD 1912/4885PPARA 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.