Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816560 | 0.91 | HSD17B1 (0.44) | HSD17B1HSD17B2NPC1RAB9A | |
| SCHEMBL3809473 | 0.90 | HSD17B1 (0.49) | HSD17B1HSD17B2 | |
| SCHEMBL3811062 | 0.89 | HSD17B1 (0.43) | HSD17B1HSD17B2NPC1RAB9A | |
| SCHEMBL3816661 | 0.88 | HSD17B1 (0.45) | HSD17B1HSD17B2 | |
| SCHEMBL3809493 | 0.87 | HSD17B1 (0.39) | HSD17B1HSD17B2 | |
| SCHEMBL3815623 | 0.87 | HSD17B1 (0.39) | HSD17B1HSD17B2 | |
| SCHEMBL3807545 | 0.87 | HSD17B1 (0.46) | HSD17B1HSD17B2 | |
| SCHEMBL2157509 | 0.85 | HSD17B1 (0.41) | HSD17B1HSD17B2 | |
| SCHEMBL3812912 | 0.85 | HSD17B10 (0.39) | HSD17B1HSD17B2 | |
| SCHEMBL3811982 | 0.84 | HSD17B1 (0.40) | HSD17B1HSD17B2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |