Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381757 | 0.83 | TDP1 (0.42) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL23812201 | 0.79 | TDP1 (0.47) | TDP1PPARGNR2E3NCOR2CA12 | |
| SCHEMBL16478559 | 0.79 | TDP1 (0.47) | TDP1PPARGNR2E3NCOR2CA12 | |
| SCHEMBL903551 | 0.79 | TDP1 (0.38) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL10047699 | 0.78 | TDP1 (0.41) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL10047677 | 0.78 | TDP1 (0.41) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL7877998 | 0.78 | TDP1 (0.50) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL30894392 | 0.78 | TDP1 (0.50) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL4970908 | 0.78 | TDP1 (0.62) | TDP1PPARGNR2E3NCOR2CA12 | |
| SCHEMBL14617992 | 0.75 | TDP1 (0.57) | TDP1PPARGNR2E3NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408783-A2 | BIOMOLECULAR LABELLING USING MULTIFUNCTIONAL BIOTIN ANALOGUES | University Of Nottingham (GB) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106347-A2 | BIOMOLECULAR LABELLING USING MULTIFUNCTIONAL BIOTIN ANALOGUES | UNIVERSITY OF NOTTINGHAM (GB) | 2010-09-23 | — | — | WO | disclosed |