Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HLCS | P50747 | 3/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970908 | 0.82 | TDP1 (0.62) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL31297012 | 0.78 | TDP1 (0.52) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL12922366 | 0.77 | TDP1 (0.41) | TDP1L3MBTL1MEN1ABL1LMNA | |
| SCHEMBL381481 | 0.75 | TDP1 (0.51) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL21493643 | 0.74 | TDP1 (0.52) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL3423752 | 0.73 | TDP1 (0.58) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL565879 | 0.72 | TDP1 (1.00) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL21488759 | 0.72 | TDP1 (1.00) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL20844951 | 0.72 | TDP1 (1.00) | TDP1PPARGNR2E3NCOR2L3MBTL1 | |
| SCHEMBL10171691 | 0.72 | TDP1 (1.00) | TDP1PPARGNR2E3NCOR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7172877-B2 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-02-06 | — | — | US | disclosed |